Private Longevity Initiative

The House of Evolution

A members-only longevity community combining gene expression therapy (including Follistatin and Klotho), stem cell therapy, and small-group experiences in destinations around the world.

Next-Generation Protocols

Three Paths to Your Next Evolution

Two glass vials resting on a blue Minicircle Klotho box.

Gene Expression Therapy

Access to emerging gene technologies designed to enhance human performance and healthy aging, including Follistatin and Klotho.

A syringe injects small blue particles into a field of large, spherical biological cells.

Stem Cell Educator Therapy

Access to a first-of-its-kind immune education technology designed to help restore healthier immune balance using your own immune cells. Backed by more than 25 years of scientific research.

A group of people lying on yoga mats in a glass-walled studio while an instructor sits at the front.

Extraordinary Experiences

Small-group journeys combining biohacking, longevity science and ancient healing. Locations include Ecuador and Kenya.

The Process

How The House of Evolution works

01

Apply.

Tell the team your goals and talk through what this means for you.

02

Join.

A $5,000 annual membership holds your place and credits toward your first annual session.

03

Choose your session.

Pick your small-group session in a destination like Cancun, Quito, or Dubai.

04

Receive your therapy.

A credentialed medical team guides you through a private session built on Minicircle’s non-viral technology.

05

Build on it.

Members get first access to new therapies, preferred pricing, and priority booking.

Cellular Reprogramming

What is gene expression therapy?

Your DNA is a USB drive that holds the instructions your cells run on right now. Gene expression therapy adds a second drive with new instructions that tell your cells to make more of the compounds your body made when you were younger. I have done it myself.

The session takes a few minutes, uses no viruses, and requires no downtime. Your cells keep following the new instructions for months, making the proteins those instructions encode.

Each therapy carries a different set of instructions.

Available Now

Follistatin

Supports lean muscle, strength, bone density, and physical resilience.

Coming Soon

Klotho

Supports cognitive performance and a younger biological profile.

Observed Outcomes

Observed outcomes from current therapies include:

Increases in cognitive performance

Increased bone density

Reduced body fat

Up to ~9 years reduction in biological age

A Note from Dave Asprey

I have worked directly with the scientists building these technologies, and have done this gene therapy myself. Apply and we’ll talk through what this could do for you.

Membership Intake

Apply for Access

House of Evolution is private and application-only. Access is limited to a small number of individuals each session to ensure precision, discretion and a high level of care.

The Team

Our team has done every therapy in this program themselves.
You are not going first. You are going next.

Dave Asprey

A smiling man with short brown hair, wearing a black button-up shirt and two necklaces, stands in front of a plain light gray background.

Father of Biohacking, 4x NYT Bestselling Author, and Podcast Host with Over 500 Million Downloads

Dr. Tim Cook

A smiling middle-aged male doctor wearing glasses and a stethoscope over a white shirt and blue vest.

World Leader in Longevity Medicine and Former Personal Physician to Two Heads of State

Marc Kielburger

Headshot of a smiling man wearing a black shirt against a dark background.

NYT Bestselling Author, Speaker, Co-Founder of the Dalai Lama Center and Certified Health Coach

Clinical Research

Read the Science

Explore peer-reviewed clinical studies and human trial data behind our longevity protocols.

Klotho & Follistatin 2026 Studies

Report of Preliminary Findings — Non-Viral Gene Delivery

Read Study

Follistatin One-Year Human Study

Nonviral Plasmid-Delivered Follistatin Can Last at Least One Year in Humans

Read Study

Body Composition & Epigenetic Age Study

Nonviral Follistatin Gene Therapy Improves Body Composition and Lowers Epigenetic Age

Read Study
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