EP 1289

1289. Should You Eat Dirt? The “Healthy” Foods Destroying Your Gut – Dr. Josh Axe

In this episode of The Human Upgrade, Host Dave Asprey sits down with functional medicine pioneer Dr. Josh Axe to expose why some of today’s most popular “healthy” foods are quietly destroying your gut and hormones. They unpack the hidden dangers of depleted soil, industrial farming, and synthetic supplements—and reveal how regenerative agriculture can rebuild your body from the ground up. You’ll learn why testosterone is collapsing in both men and women, how birth control impacts thyroid and mitochondrial health, and why biblical farming principles could hold the key to modern longevity. This conversation blends science, spirituality, and high-performance biohacking for a deeply personal look at what it really means to nourish the body, mind, and soil. 

Subscribe To The Human Upgrade

In this Episode of The Human Upgrade™...

You’ve been told to eat clean, but what if your “healthy” foods are wrecking your gut, crushing your hormones, and aging you faster? This episode exposes the nutrient-depleted truth behind modern diets, soil erosion, and why regenerative farming might be the key to reversing chronic disease, boosting mitochondria, and rebuilding your biology from the ground up. 

Host Dave Asprey sits down with Dr. Josh Axe, a trusted pioneer in functional medicine, bestselling author, and co-founder of Ancient Nutrition. Dr. Axe bridges the gap between biblical farming, ancestral nutrition, and modern science to explain how your food and even your supplements may be harming your human performance, digestion, and brain health. With clinical insights, personal stories, and science-backed tools, he shares what to eat instead if you want real longevity, energy, and healing. 

They dig into the collapse of soil nutrients, how monocropping damages the microbiome, and why organic food standards may be outdated. You’ll learn how regenerative agriculture rebuilds the earth and your gut, and why biohacking starts with dirt, not pills. Plus, they explore the hormonal chaos caused by seed oils, plastics, blue light, sleep disruption, and even birth control, especially in relation to testosterone loss in men and women. 

This episode also touches on biblical nutrition, fasting cycles, natural nootropics, testosterone-supporting peptides, the dangers of synthetic vitamins, and the future of real-time self-quantification. From poop-powered farming to smarter sourcing, it’s a wild ride into how food, faith, and farming affect every part of your biology. 

This is essential listening for anyone serious about biohackingneurohackinglongevityUpgrade LabsDanger CoffeeSmarter Not Harder, and understanding the real root of disease and dysfunction. 

 

You’ll Learn: 

  • Why regenerative farming beats “organic” for health and the planet
  • How depleted soil is linked to hormone imbalances and chronic disease
  • What birth control is doing to testosterone, fertility, and mitochondrialhealth
  • Why your supplements may just be “expensive pee”
  • The truth about biblical farming and why dirt still matters
  • How to support testosterone naturally with diet, peptides, and habits
  • Why sleep optimization, mineral balance, and circadian alignment are key for healing

 

Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade is the top podcast for people who want to take control of their biology, extend their longevity, and optimize every system in the body and mind. Each episode features cutting-edge insights in health, performance, neuroscience, supplements, nutrition, hacking, emotional intelligence, and conscious living. 

Episodes are released every Tuesday and Thursday, where Dave asks the questions no one else dares, and brings you real tools to become more resilient, aware, and high performing. 

 

 

SPONSORS: 

BON CHARGE | Go to https://boncharge.com and use code DAVE for 15% off.  

– Zbiotics | Go to https://zbiotics.com/DAVE for 15% off your first order 

 

“Today, you can go to Whole Foods and buy something labeled organic—and it’s still absolute garbage.”

Josh Axe

  • 00:00 Trailer

Quick hook on testosterone, food, and why ‘eating dirt’ might not be crazy. 

  • 00:52 Intro

Dave introduces the episode’s central question about “healthy” food and gut health. 

  • 01:01 From Medicine to Farming

Josh shares his journey from chiropractic care to regenerative agriculture. 

  • 02:21 Regenerative Farming

How depleted soil affects nutrient density and long-term human health. 

  • 03:36 Fixing Modern Agriculture

Solutions to topsoil loss, monocropping, and industrial food damage. 

  • 05:43 Biblical Farming Meets Modern Science

Blending ancient wisdom with soil science and animal grazing. 

  • 08:23 The Truth About Organic Food

Why “organic” might be outdated and what standards are better. 

  • 12:41 What’s Causing the Testosterone Crash

The top reasons men and women are losing testosterone fast. 

  • 18:07 Hormonal Birth Control

The overlooked risks of long-term birth control on thyroid and fertility. 

  • 27:37 New Hormone Replacement

Breakthroughs in testosterone therapy that avoid harmful side effects. 

  • 29:58 The Future of Health Tracking

Coming tech for real-time data on hormones, nutrients, and microbiome. 

  • 32:00 What Is Biblical Farming?

Josh defines the foundational principles found in scripture-based farming. 

  • 33:38 Biblical Principles of Nutrition

Foods prioritized in the Bible and their biological impact. 

  • 33:55 Foods Most Mentioned in the Bible

Olives, figs, pomegranates, meat, and the deeper meaning behind them. 

  • 35:17 Pork, Parasites, and Dietary Laws

Why pork is controversial in both religious and health contexts. 

  • 37:29 Chinese Medicine’s View on Pork

What ancient Eastern medicine says about pork and health conditions. 

  • 39:36 Did the Flood Shorten Human Lifespan?

A look at lifespan decline in scripture and potential environmental triggers. 

  • 42:26 Biodynamic Farming and Spirituality

Exploring whether biodynamic agriculture is spiritual, evil, or misunderstood. 

  • 54:27 Fatherhood and Words That Heal

How parenting and affirmations shape resilience and emotional health. 

  • 56:21 What Josh Feeds His Kids

The real foods his family eats and how they handle oxalates and grains. 

  • 01:03:41 Mental Health, Faith, and Healing

The powerful link between emotional well-being, belief, and physical health. 

  • 01:05:36 Final Thoughts

Dave and Josh wrap with practical takeaways and spiritual reflections. 

 

 

 

 

 

Resources:  

Enjoy the show!

LISTEN:

“Follow” or “subscribe” to The Human Upgrade™ with Dave Asprey on your favorite podcast platform.

REVIEW: 

Go to Apple Podcasts at daveasprey.com/apple and leave a (hopefully) 5-star rating and a creative review.

FEEDBACK:

Got a comment, idea or question for the podcast? Submit via this form!

SOCIAL:

Follow @thehumanupgradepodcast on Instagram and Facebook.

JOIN: 

Learn directly from Dave Asprey alongside others in a membership group: ourupgradecollective.com.

Subscribe To The Human Upgrade

Similar Episodes

podcast-divider-bottom.png

Subscribe To The Human Upgrade

BOOKS

4X NEW YORK TIMES
BEST-SELLING SCIENCE AUTHOR

AVAILABLE NOW

Smarter
Not Harder

Smarter Not Harder: The Biohacker’s Guide to Getting the Body and Mind You Want is about helping you to become the best version of yourself by embracing laziness while increasing your energy and optimizing your biology.

If you want to lose weight, increase your energy, or sharpen your mind, there are shelves of books offering myriad styles of advice. If you want to build up your strength and cardio fitness, there are plenty of gyms and trainers ready to offer you their guidance. What all of these resources have in common is they offer you a bad deal: a lot of effort for a little payoff. Dave Asprey has found a better way.
media-section-06-img.png

Also Available

footer-line-img.png

Start hacking your way to better than standard performance and results.

Receive weekly biohacking tips and tech by becoming a Dave Asprey insider.

By sharing your email, you agree to our Terms of Service and Privacy Policy