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In this episode of The Human Upgrade, Dave Asprey sits down with Dr. Anurag Singh, Chief Medical Officer at Timeline Nutrition and a leading expert in mitochondrial and cellular health, to uncover the groundbreaking potential of Urolithin A. Dr. Singh delves into the science of how this revolutionary postbiotic enhances mitochondrial function, combats inflammaging, and restores youthful energy. Beyond the research, Dr. Singh shares practical strategies for improving immune resilience, reducing inflammation, and boosting overall vitality. This episode is packed with cutting-edge insights and actionable tips for anyone aiming to upgrade their energy, longevity, and cellular health.
Have we finally discovered the key to youthful energy, longevity, and cellular health?
In this episode, Dave Asprey sits down with Dr. Anurag Singh, Chief Medical Officer at Timeline Nutrition and a leading expert on mitochondrial health, cellular regeneration, and anti-aging science. With over 20 years of research, 50 clinical trials, and 15 patents under his belt, Dr. Singh unpacks the groundbreaking science behind Urolithin A, a revolutionary postbiotic that boosts mitochondrial function, enhances immune system resilience, and combats chronic inflammation.
This episode goes beyond cutting-edge science. Dr. Singh reveals practical, real-world strategies to combat “inflammaging”—the chronic, low-grade inflammation that accelerates aging. Learn how fasting, gut health, and mitochondrial boosters like Urolithin A can rejuvenate your cells, fight fatigue, and supercharge your energy, vitality, and longevity.
Here’s what you’ll learn in this episode:
Dave Asprey sets the stage by explaining why mitochondria are central to longevity, energy production, and overall health.
Dr. Anurag Singh discusses how mitochondria influence immune system function and resilience against aging.
Learn about inflammaging—chronic low-grade inflammation that accelerates aging—and how it impacts immune health.
Explore modern methods for assessing inflammation and immune system decline, including biomarkers like C-reactive protein and interleukins.
Discover the science behind Urolithin A, its role in enhancing mitochondrial health, and how it combats cellular aging.
Dr. Singh explains optimal dosing strategies for Urolithin A, its absorption, and how it delivers measurable benefits.
Hear how Urolithin A supports athletic recovery, reduces inflammation, and improves muscle health in high-performing athletes.
Learn about Urolithin A’s effects on skin aging, hydration, and collagen preservation for visible anti-aging results.
Dr. Singh explains how matrix metalloproteinases (MMPs) degrade collagen and accelerate skin aging, and how Urolithin A helps combat this process.
Dave shares his personal recovery journey after high MMP levels, including strategies that helped him feel better faster.
Discover how MMP levels can indicate tissue aging and inflammation, and the potential for integrating them into longevity panels.
A closer look at clinical trials showing Urolithin A’s ability to reduce wrinkles, improve hydration, and enhance skin elasticity.
From metabolic health to gut microbiome support, Dr. Singh explores the far-reaching potential of Urolithin A.
Discussion of ongoing trials investigating how Urolithin A enhances mitochondrial function in the brain to improve cognitive health.
Tips on stacking Urolithin A with omega-3s, CoQ10, and other supplements to maximize overall health and performance.
Dr. Singh highlights the critical role of omega-3 fatty acids in mitochondrial function and heart health.
Explore how Urolithin A synergizes with ketones and MCTs to optimize energy metabolism and mitochondrial health.
Wrapping up the episode, Dr. Singh emphasizes the importance of Urolithin A as a foundational supplement for longevity and health optimization.
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