In this episode of The Human Upgrade, Host Dave Asprey sits down with primal health pioneer Mark Sisson to reveal why walking smarter—not longer—is the key to lasting health and performance. They dive into a Japanese walking interval method that beats 10,000 steps a day, the overlooked role of foot mechanics in brain-body optimization, and how minimalist movement unlocks longevity. You’ll learn why Mark trains just 20 minutes a week, how to reverse foot dysfunction naturally, and why intuitive biohacking always outperforms perfectionism.
Most people think 10,000 steps a day is the gold standard for health, but it’s outdated, inefficient, and often damaging. In this episode, you’ll discover a smarter, faster way to walk for longevity, fat burning, and total body resilience.
Host Dave Asprey sits down with Mark Sisson, bestselling author, primal health pioneer, and founder of Primal Kitchen. With over 40 years at the forefront of fitness and ancestral health, Mark has helped millions rethink everything they thought they knew about cardio, running, metabolism, and movement. He was one of the first to challenge the chronic cardio myth, helped popularize ketosis and fat-adapted performance, and now returns with a new message: walking right, not more, is one of the most powerful biohacks for human performance and aging.
They dive into the Japanese walking interval method that outperforms 10,000 steps, and explore the critical link between foot health, barefoot shoes, and the brain-body connection. Mark also shares why he trains just 20 minutes a week, why too much saturated fat might backfire, and why performance should never come at the cost of your mitochondria. You’ll learn how to build muscle and endurance with less effort, how to reverse foot dysfunction with every step, and how to age with strength, intuition, and freedom.
This episode hits hard on biohacking, functional movement, longevity, self-quantification, and the real science of walking smarter, not longer. It’s also packed with insights on ketosis, nootropics, sleep optimization, and why perfectionism ruins health gains.
If you’re serious about Smarter Not Harder strategies, tuning into your body, and reclaiming your natural performance potential, don’t miss this one.
You’ll learn:
Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade is the top podcast for people who want to take control of their biology, extend their longevity, and optimize every system in the body and mind. Each episode features cutting-edge insights in health, performance, neuroscience, supplements, nutrition, hacking, emotional intelligence, and conscious living.
Episodes are released every Tuesday and Thursday, where Dave asks the questions no one else dares, and brings you real tools to become more resilient, aware, and high performing.
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A preview of what you’ll learn about walking, foot health, and minimalist movement.
Dave Asprey introduces the episode and what’s at stake with how we move.
From elite endurance athlete to Primal Kitchen and footwear innovator.
How Mark helped shape the online wellness revolution.
The dangers of chronic cardio and how to rethink endurance training.
Why strong, functional feet are essential for whole-body resilience.
The surprising benefits of ditching traditional shoes.
Mark reveals his new minimalist shoe company and its mission.
How nutrition affects inflammation, healing, and long-term mobility.
The problem with fashionable shoes and how to choose better.
Dave and Mark share their favorite minimalist shoe experiences.
Behind the scenes of starting a performance-first shoe company.
Why most shoes prioritize looks over your longevity.
Mark’s go-to exercises for rebuilding foot strength and alignment.
How ancient footwear design supports modern mobility.
The neurological benefits of mindful, structured walking.
How to eat for muscle retention, fat burn, and long-term health.
Mark’s top strategies for staying strong, lean, and high-performing.
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Smarter Not Harder: The Biohacker’s Guide to Getting the Body and Mind You Want is about helping you to become the best version of yourself by embracing laziness while increasing your energy and optimizing your biology.
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