Dr. Doug McGuff, MD: Body By Science – #26

Dave Asprey
body by science

Doug McGuff, MD, is an author, personal trainer, and practicing medical professional.  In an effort to prevent, and not just treat disease, Dr. McGuff has developed a unique system of weight training that promises results in as little as 12 minutes a week.  Along with John Little, a renowned strength and conditioning coach, Dr McGuff wrote Body By Science, one of the best books on strength, health, and fitness you’re likely to find.  Dr. McGuff comes on the show to talk about how you can enhance your performance, health, and longevity with an exercise program that takes only 12 minutes a week.

What We Cover

  1. How did you get interested in health and fitness?
  2. Can you share your definition of health, fitness, and exercise so we are all on the same page?
  3. Would you talk about how to balance the relationship between anabolism and catabolism to improve health and performance?
  4. What are the criteria for something to count as exercise?
  5. Can you talk about how exercise is a drug?
  6. Do you think running marathons or doing Ironmans counts as exercise?  Or should it be considered it’s own entity?
  7. What do you think of what most people refer to as “cardio.” Do you need to do “aerobic” exercise to keep your heart and lungs healthy?
  8. What role does nutrition play in improving body composition?
  9. What do you think are some of the flaws of barbell training?
  10. Do you think Crossfit is a good way to build strength?
  11. What do you think of explosive plyometric/olympic type lifting?  Will it really help the average lifter?
  12. Is stretching and mobility type work necessary?
  13. Is balance training like bosu balls and standing on one foot necessary to improve balance or proprioception?
  14. If someone is training for a specific sport, do these principles still apply?
  15. What is the best way to fatigue a muscle and produce growth?
  16. Can you talk about the specifics of your “Big 5” workout?
  17. If progress stalls, should you do more exercise or less?
  18. Does this mean you can’t train more than once a week?  What about other activities, do those have to be limited as well?
  19. Is this kind of training safe or useful for the elderly or people who lack experience?

Links From The Show


Body By Science by Dr. Doug McGuff & John Little



Consulting Requests for Dr. Doug McGuff (call 864-886-0200)

Food & Supplements

Upgraded™ Glutathione

Vitamin D3

Vitamin C


Upgraded™ Whey Protein

Flaxseed Lignin Extract

Cod Liver Oil/Butter Oil Blend

Kerrygold Grass-Fed Butter

Grass-Fed Meat


The 4-Hour Body by Timothy Ferriss

Body By Science by Dr. Doug McGuff & John Little

The Cholesterol Myths by Uffe Ravnskov

The Better Baby Book by Dave Asprey


Link to BBC article on sleep.

Wellnessfx Post (with a $100 discount!)

Dr. Ray Kurzweil

Listener Q & A Summary

  1. What supplements can you take to boost immune function?
  2. Should you sleep twice a day instead of once?
  3. Are flax seeds safe?

Biohacker Report

“Orbital prefrontal cortex volume predicts social network size: an imaging study of individual differences in humans.”

“Quality control, accuracy, and prediction capacity of dual energy X-ray absorptiometry variables and data acquisition.”

“Exposure to soy-based formula in infancy and endocrinological and reproductive outcomes in young adulthood.”

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Dave Asprey

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