Regena Thomashauer, known worldwide as Mama Gena, bestselling author and founder of the School of Womanly Arts, joins Host Dave Asprey to break down why she stopped looking forward to each day as a child growing up in an abusive household, how a single class in pleasure and embodiment pulled her out of years of repression and into a life-changing encounter with her own reflection, why she left a career pursuit to live inside a sex commune for five years studying female orgasm, how oxytocin, prolactin, and endorphins act as the body’s own medicine cabinet for processing trauma and stress, the meaning behind her new book On Our Knees and what it means to surrender with reverence instead of defeat, the forgiveness work she did after profound personal betrayal, the difference between righteous anger and stridence and why one moves you forward while the other keeps you stuck, why calling female anatomy by its correct name matters for a girl’s relationship to her own body, the Daoist practice of semen retention and its reported link to energy and longevity in men, how a person can create a felt sense of safety in another simply through energetic presence, and the ancient orgasm equations that mark the upper limits of pleasure for men and women. Essential listening for anyone serious about biohacking, human performance, longevity, functional medicine, embodiment, nervous system regulation, and reclaiming pleasure as a source of power.
The Orgasm Code: How Pleasure Rewires Your Nervous System for Longevity & Healing | Regena Thomashauer (Mama Gena)
Most people think pleasure is a distraction from performance. This episode proves the opposite: your orgasm is a biohacking tool wired directly into your nervous system, your hormones, and your longevity.
Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR
Host Dave Asprey sits down with Regena Thomashauer, known worldwide as Mama Gena, founder and CEO of the School of Womanly Arts and a New York Times bestselling author. For over three decades she has taught hundreds of thousands of women how to reclaim pleasure as a source of power, and her work has redefined what modern feminism and embodiment look like in practice.
Dave and Regena break down the actual biology behind orgasm: the oxytocin, prolactin, and endorphin cascade that shifts the body out of fight or flight and into repair, the role of sleep optimization in processing trauma, and how chronic disconnection from pleasure keeps people stuck in survival mode instead of human performance mode. They dig into semen retention research and its link to longevity and anti-aging, why shame around the body blocks neuroplasticity and emotional healing, and how learning to regulate arousal, rage, and surrender is its own form of nervous system hacking. This is a masterclass in reclaiming a part of your biology most people were never taught to understand, let alone optimize.
This is essential listening for anyone serious about biohacking, human performance, brain optimization, functional medicine, longevity, and building a body and mind that can hold more pleasure, more power, and more presence.
You’ll Learn:
Keywords: Mama Gena, Regena Thomashauer, On Our Knees book, Pussy A Reclamation, School of Womanly Arts, orgasm and oxytocin, prolactin endorphins orgasm, extended orgasm training, semen retention benefits, Daoist orgasm practices, Lafayette Morehouse, truth tantrum tender tantrum, clitoris anatomy explained, vulva versus vagina, goddess archetypes women, embodiment practice trauma, devotion versus attention, Dave Asprey Mama Gena, female pleasure biohacking, nervous system relaxation orgasm
Resources:
00:00 – Intro
Dave and Mama Gena open with a blessing before diving into the conversation.
01:21 – What makes a feminist
Mama Gena explains her version of feminism as a devotion to women fully expressing their desire and power.
07:24 – Orgasm saved my life
She shares how growing up in an abusive household led her to a class that changed the course of her life through pleasure and embodiment.
16:34 – The body’s medicine cabinet
They discuss how oxytocin, prolactin, and endorphins act as the body’s own natural pharmacy for healing and connection.
20:08 – Meaning of On Our Knees
Mama Gena unpacks the title of her new book and what it means to surrender with reverence rather than defeat.
27:34 – Betrayal and forgiveness
Dave and Mama Gena open up about personal betrayals, including Dave’s ouster from his own company, and the forgiveness work that followed.
37:05 – Righteous anger vs. stridence
Mama Gena breaks down the difference between grounded, purposeful anger and reactive, victim-driven complaint.
47:02 – Semen retention practice
Dave explains the Daoist approach to semen retention and its reported effects on energy, focus, and relationships.
52:51 – Energetic heart connection
Dave demonstrates how he creates a felt sense of safety and openness with someone through energetic presence.
01:00:53 – Daoist orgasm equations
They compare ancient formulas for orgasmic frequency and duration in men and women, and what they reveal about pleasure and surrender.
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