In this episode of The Human Upgrade, Host Dave Asprey talks with Rowena Gates, biophysicist and co-founder of NanoVi, to reveal how structured water and mitochondrial repair are transforming recovery, energy, and longevity. Backed by research in redox signaling and protein repair, NanoVi uses energized water vapor to enhance oxygen efficiency, neuroplasticity, and cellular regeneration. Dave and Rowena explore how structured water boosts VO? max, accelerates healing, and integrates with biohacks like cold therapy, fasting, and sleep optimization to extend lifespan and upgrade human performance.
What if you could improve your mitochondria, oxygen efficiency, and recovery in just 20 minutes a day—by breathing energized water? This episode explores one of the most surprising breakthroughs in biohacking and how it can help you live longer, think clearer, and perform better.
Host Dave Asprey talks with Rowena Gates, co-founder of NanoVi, a therapeutic device backed by biophysics research that supports protein repair and mitochondrial communication. Her work reveals how structured water inside your cells drives neuroplasticity, cellular regeneration, and stress resilience—offering a new pathway to recovery, energy, and longevity.
You’ll learn how structured water affects mitochondrial efficiency, how it compares to recovery methods like cold therapy and fasting, and why improved VO? max may correlate with a longer lifespan. Dave and Rowena also explore how NanoVi stacks with supplements, nootropics, ketosis, and functional medicine to enhance brain optimization, metabolism, and human performance.
You’ll Learn:
They explore how structured water, mitochondrial repair, and recovery science intersect to create a smarter approach to health and longevity. You’ll also learn how optimizing cellular communication, oxygen efficiency, and stress resilience can accelerate healing, improve focus, and extend lifespan.
This is essential listening for anyone serious about biohacking, human performance, and longevity, and for those who want to understand how functional biology and mitochondrial science are redefining recovery, energy, and aging.
Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights in health, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living.
New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient.
Keywords: NanoVi, Structured water, Energized water, Biohacking, Dave Asprey, Mitochondrial repair, Mitochondrial communication, Human performance, Longevity, Recovery science, Oxidative stress, Protein repair, Redox signaling, Cellular hydration, Functional medicine, VO? max, Neuroplasticity, Brain optimization, Cellular energy, Stress resilience, Cold therapy, Fasting, Sleep optimization, Breathwork, Nootropics, Metabolism, Oxygen efficiency, ATP production, Cellular regeneration, Anti-aging, Smarter Not Harder
**To level up your mitochondria with a NanoVi: visit https://eng3corp.com/dave/ **
0:00 — Trailer
A preview of how structured water and mitochondrial science are changing biohacking.
1:25 — Introduction to NanoVi
Dave and Rowena explain what NanoVi is and how it supports the body through energized water.
4:01 — How to Use NanoVi
Practical guidance on daily use, session timing, and how to integrate it into your routine.
6:23 — Understanding Ordered Water
Rowena breaks down the science behind structured water and how it forms in the body.
9:16 — Scientific Evidence & Studies
How NanoVi’s effects are measured through biophysics and validated human trials.
13:02 — Pricing & Accessibility
Discussion of the different NanoVi models, cost, and availability for consumers and clinics.
15:02 — Mitochondrial Function & MiScreen Results
Data showing NanoVi’s impact on mitochondrial connectivity and energy efficiency.
19:55 — Brain Function & Cognitive Benefits
How improved blood flow and oxygen metabolism boost brain performance.
23:47 — How Ordered Water Works
Explaining the energy transfer process that helps proteins fold and cells repair.
27:34 — Cellular Communication & Fascia
Exploration of how water, fascia, and mitochondrial signaling affect human performance.
30:14 — Heart Rate Variability & Stress Reduction
Study results showing a 45% drop in stress and major gains in parasympathetic balance.
34:54 — Athletic Performance & Recovery
How athletes use NanoVi for lactate reduction, faster recovery, and increased endurance.
38:52 — Mental Health & Sleep Benefits
Evidence linking NanoVi to better mood, reduced anxiety, and deeper restorative rest.
42:00 — Supplement Stacking
Dave and Rowena share ideal supplements that synergize with mitochondrial enhancement.
45:50 — Deep Sleep & Parasympathetic State
Exploring how NanoVi before bed can enhance relaxation and sleep quality.
48:48 — Chronic Conditions & Fatigue
How mitochondrial repair supports recovery from long COVID, chronic fatigue, and burnout.
51:54 — Meditation & Brain Training
Integrating NanoVi into meditation and neurofeedback training for mental resilience.
55:42 — Brain Injury & Resilience
Using NanoVi for pre-treatment and recovery in concussion and brain trauma.
59:36 — Conclusion & Where to Get It
Final insights on resilience, longevity, and how to access the NanoVi device.
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