Discover how fear silently controls your life—and how courage can set you free. In this compelling conversation, Ryan Holiday, bestselling author of Courage Is Calling, joins Dave Asprey to explore the transformative power of courage in facing fear, making bold choices, and finding true purpose. Drawing on Stoic philosophy, historical insights, and modern challenges, this episode delivers actionable wisdom to help you conquer self-doubt, embrace responsibility, and live a life of meaning and impact.
Fear is quietly running your life—and it’s holding you back from the purpose and success you deserve. In this episode, we revisit Dave chatting with one of the keynote speakers for the Biohacking Conference 2025, Ryan Holiday, the bestselling author of Courage Is Calling, to tackle the one thing standing between you and your potential: fear.
Why should you listen? Because fear is the root cause of procrastination, self-doubt, and the endless excuses that keep you stuck. Ryan reveals why courage isn’t just about bravery—it’s about making the hard choices that align with your purpose, even when the stakes are high.
Drawing on powerful examples from history and modern life, Ryan explains how fear can be transformed into a catalyst for action and why embracing discomfort is the key to unlocking true freedom. If you’ve ever felt paralyzed by uncertainty, this episode will give you the tools and perspective to take control, face your fears, and create the life you’re meant to live.
Why This Episode Matters:
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Dave introduces Ryan Holiday and sets the stage for a conversation on courage and fear.
Insights into Ryan’s books, including Courage Is Calling, and his approach to modern Stoicism.
What courage truly means and how it applies to everyday life.
How historical figures like Florence Nightingale transformed fear into action.
Practical ways to apply ancient Stoic principles to today’s challenges.
Exploring courage, temperance, justice, and wisdom as a cohesive framework.
Why admitting errors requires courage and how it leads to growth.
Ryan shares personal insights from opening a bookstore amid global uncertainty.
How bold decision-making shapes success and fulfillment.
Lessons from Netflix’s evolution and moments of missed opportunity.
The importance of standing up for principles, even in the face of adversity.
A nuanced discussion on balancing societal health and individual rights.
Ryan and Dave examine the complexities of collective responsibility.
Why embracing responsibility is essential for a functioning world.
How questioning beliefs and assumptions leads to personal and societal growth.
Ryan shares his strategies for spreading meaningful ideas in an attention-driven age.
Wrapping up with Ryan’s advice on how courage can transform lives and communities.
Resources:
2025 Biohacking Conference – https://biohackingconference.com/2025
Ryan Holiday’s Website – https://ryanholiday.net
Daily Stoic Website – https://dailystoic.com/
Ryan Holiday’s Book: Courage Is Calling – https://a.co/d/czEfCXC
Ryan Holiday’s Instagram – https://www.instagram.com/ryanholiday
Danger Coffee – https://dangercoffee.com
Dave Asprey’s Website – https://daveasprey.com
Dave Asprey’s Book: Smarter Not Harder – https://daveasprey.com/books
Dave Asprey’s Linktree – https://linktr.ee/daveasprey
Upgrade Collective: Join The Human Upgrade Podcast Live – https://www.ourupgradecollective.com
Own an Upgrade Labs – https://ownanupgradelabs.com
Upgrade Labs – https://upgradelabs.com
40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement – https://40yearsofzen.com
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