Live Longer: 5 Simple Anti-Aging Biohacks


I plan to live to 180 years old. 

Usually people balk when I say that, but it’s not as crazy as it sounds. Thanks to the groundbreaking work of anti-aging researchers in the last decade, aging no longer looks like an unavoidable part of life. Scientists are beginning to view it as a disease, and they’re already figuring out the cure. 

There are a lot of biohacks out there that can slow down aging. Some of them we’ve known about for years—eating good food and working out are two basic ones—but there are also a lot of lesser-known ways to live a longer, better life. 

Here are 5 simple longevity hacks that you can start today. 

1. Nicotinamide Riboside

There are a lot of anti-aging supplements out there that don’t work. Nicotinamide riboside (NR) is one of the few that actually does. 

NR is a specialized form of vitamin B that protects your brain mitochondria from oxidative stress and increases their energy output. 

Your mitochondria are the power plants of your cells. When your mitochondria are stronger, your cells produce more energy, and everything in your body works better—you’re mentally sharper, you have more physical strength and endurance, you don’t feel fatigued, and so on. 

NR optimizes the ratio of NAD+ and NADH, which gives your mitochondria more access to energy and makes them less susceptible to damage over time[*][*]. 

This is one of those supplements that you can actually feel working. You’ll be sharper and will have more energy within a couple hours of taking it. I recommend Unfair Advantage, which gives you the right amount of NR in the most bioavailable form, along with cofactors that help your mitochondria use it better. 

2. Fasting

Fasting activates dozens of anti-aging pathways in both your body and brain, keeping you young from the inside out. 

Research shows that fasting decreases oxidative stress on your body and increases lifespan[*]. It also makes you live a better life, not just a longer one: fasting when you’re older decreases frailty[*] and keeps your brain sharp[*]. 

You can start fasting right now with a simple intermittent fasting guide

3. Boosting Collagen (Not Just with Protein Powder)

Collagen is the main type of protein in your skin, hair, and connective tissue. It’s also an important component of your bones. 

As you get older, collagen breaks down and your body stops producing it as quickly as it did when you were younger. That’s one reason why you get wrinkled and sagging skin and your joints and bones become weaker as you age. 

With the right biohacks, you can stimulate collagen production and keep your levels stable as you get older. 

Three of the most powerful ways to stimulate collagen are:

  • Collagen protein. Eating collagen protein powder stimulates your body’s own collagen production and improves skin hydration and smoothness, as well as joint health[*]. Mix a scoop into your morning coffee or a smoothie (or just drink it with water). 
  • Cryotherapy. Intense cold boosts collagen production and does a bunch of other good things for you (like decreasing inflammation)[*]. 
  • Vitamin C. Vitamin C is an essential cofactor for collagen production. Try taking 1000 mg every morning to increase your collagen levels. 


Exercise in general is a powerful anti-aging tool, and high-intensity interval training (HIIT) in particular is your best option for longevity. HIIT involves doing bursts of maximum-intensity exercise with brief rest in between. 

A 2019 study compared HIIT, weightlifting, and cardio to see which one caused the biggest shift in markers of aging, and HIIT came out on top[*]. 

5. Stem Cell Therapy

Stem cells are at the cutting edge of longevity medicine. They’re undifferentiated cells, which means they can turn into whatever kind of cell your body needs most at the time that you inject them. Stem cell therapy is a good way to clear out old or damaged cells and replace them with shiny new ones, leaving you biologically younger after treatment.

Stem cells also make your existing cells work better by stimulating anti-aging pathways. 

You’ll have to work with a doctor for stem cell treatments. They’re more involved than the other options on this list, but they’re also one of the most powerful anti-aging treatments available. 

A Longevity Protocol: the Best Way to Slow Down Aging

I want people to realize how important (and powerful) anti-aging biohacks are. The problem is that there are a lot of longevity biohacks out there, and the ones that will work best for you depend on your unique biology, epigenetics, lifestyle, medical history, and other factors that are specific to you. 

The best way to develop an anti-aging strategy is through personalized medicine, which is usually crazy expensive and is off the table for most people. 

That’s why I’ve partnered with Liv HEALTH, one of the leading anti-aging clinics in the U.S. 

Liv HEALTH gives you access to a team of doctors, practitioners, health concierges, nutritionists, and naturopaths, all working together to design a personal protocol for you based on your unique body, diagnostic testing, and biofeedback results.

Their customized protocols can include any combination of lifestyle interventions, personalized supplements and even prescription pharmaceuticals.

Liv is looking to revolutionize medical care in the US by making high-quality, proactive medicine affordable for everyone. It’s a mission I believe in, so I’ve partnered with them to offer a special deal to my readers. 

In the interim, you can get your first month of Liv HEALTH for free + 50% off your initial lab panel. 

This was a tough partnership to negotiate so I hope you’ll give Liv a try. They’re an awesome company and I believe in their mission. Top-quality preventative medicine is something everyone should be able to access. 




Not Harder

Smarter Not Harder: The Biohacker’s Guide to Getting the Body and Mind You Want is about helping you to become the best version of yourself by embracing laziness while increasing your energy and optimizing your biology.

If you want to lose weight, increase your energy, or sharpen your mind, there are shelves of books offering myriad styles of advice. If you want to build up your strength and cardio fitness, there are plenty of gyms and trainers ready to offer you their guidance. What all of these resources have in common is they offer you a bad deal: a lot of effort for a little payoff. Dave Asprey has found a better way.

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