EP 1136

1136. Variable Resistance: The Ultimate Muscle Hack

Today we’re talking about testosterone replacement and unpacking the novel concepts of progressive overload and variable resistance training with Dr. John Jaquish.

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In this Episode of The Human Upgrade™...

Today we’re talking about testosterone replacement and unpacking the novel concepts of progressive overload and variable resistance training—both methods to gain, and keep, muscle mass in your body without living in the gym.

I’m joined by strength expert, entrepreneur, past guest of the show, and PhD, John Jaquish. John has spent years researching and developing improved approaches to health. Inventor of X3, a technology that is proven to develop muscle much faster than conventional weight lifting with the lowest risk of joint injury, Dr. Jaquish’s methods are used in training the world’s most elite athletes as well as Olympians.

Aligning with the most basic tenet of biohacking, if you can achieve all of your physical or athletic goals in half the time of your competitors, why not explore the option? John is as gracious as he is informed in this one, detailing the benefits of variable resistance training and indulging me in a super deep dive into diet and nutrition experimentation, testosterone replacement therapy, and efficient muscle growth.

You’ll learn what he eats every day to look as good as he does. You’ll get repetition-count-specific recommendations on ultra-quick workout routines. And you’ll learn the very surprising amount of carbohydrates I ingest every single day (a number that will shock many of you).


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“Applying a higher level of force in stronger positions of an exercise, and a lower level of force in compromised positions of exercise, I can go to a greater level of fatigue and trigger more growth.”



Masterclass on Efficient Muscle Building

  • Who spends less time in the gym, Dave or John?
  • Three types of muscle growth 
  • Muscle size vs. strength 
  • Dave’s experience with the X3 Bar
  • John explains progressive overload
  • John’s recommended repetitions 
  • Overcoming the trolls 


How are Shaolin Monks & Gymnasts So Strong?  

  • Training for neurological strength 
  • Getting 100% of a muscle to fire 
  • Modern vs. ancient strength training 
  • Prioritizing slow repetitions 
  • Read: Smarter Not Harder by Dave Asprey
  • Digital benefits if the new X3 Bar


Testosterone Replacement Therapy (TRT)


How Protein Impacts Muscle Growth


Breakthrough Personal Research on Carbohydrates

  • Detailing Dave’s dieting experimentation
  • Risks of body fat below 4%   
  • Benefits of cycling ketosis 
  • Toxic Superfoods by Sally K. Norton
  • Eating all of the AMA’s recommended nutrients in a day


Weight Lifting is a Waste of Time

  • Test and iterate: It’s all about the results
  • Dave hints at an upcoming protein product 
  • Looking closely at efficiency of exercise 
  • The future is variable resistance 
  • Endorsed by the Miami Heat


Dave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books 

Website: jaquishbiomedical.com

Instagram: @drjaquish

YouTube: Jaquish Biomedical

Read: Weight Lifting Is a Waste of Time

Read: Osteogenic Loading: A New Modality To Facilitate Bone Density Development

How to Build Strength Faster – John Jaquish, Ph.D. #863

Building Strength Isn’t About Weight Lifting Anymore – John Jaquish, Ph.D. #862

Enjoy the show!


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Not Harder

Smarter Not Harder: The Biohacker’s Guide to Getting the Body and Mind You Want is about helping you to become the best version of yourself by embracing laziness while increasing your energy and optimizing your biology.

If you want to lose weight, increase your energy, or sharpen your mind, there are shelves of books offering myriad styles of advice. If you want to build up your strength and cardio fitness, there are plenty of gyms and trainers ready to offer you their guidance. What all of these resources have in common is they offer you a bad deal: a lot of effort for a little payoff. Dave Asprey has found a better way.

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