In this episode of The Human Upgrade, Host Dave Asprey talks with Brandon Harris, founder and CEO of Jawzrsize. Brandon shares how a shattered jaw, a 13 day coma, and months of recovery led him to discover how deeply jaw strength influences posture, airway stability, neuromuscular coordination, and cognitive performance. You will learn why weakened jaw muscles contribute to sleep apnea, poor alignment, and reduced cranial blood flow, and how targeted resistance training restores strength, improves facial structure, and supports total body function. Dave and Brandon break down real world results from jaw training, including increased jaw strength, improved TMJ balance, wrinkle reduction, better oral and gut health through enhanced saliva flow, and relief from clenching and grinding. They explore how modern soft diets shrink facial structure, why full range jaw motion matters, and how strengthening the jaw creates measurable changes in posture, proprioception, and athletic performance, while also discussing device safety, clinical findings, and why jaw training is emerging as a practical biohacking tool for longevity and human performance.
Your jaw influences far more than your face. This episode shows you how jaw strength shapes cognition, posture, airway health, sleep, metabolism, and overall human performance. You will learn how targeted jaw training increases cranial blood flow, improves neuromuscular coordination, strengthens airway stability, and stimulates facial muscles that modern diets no longer challenge.
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Host Dave Asprey talks with Brandon Harris, founder and CEO of Jawzrsize. Brandon developed the device after multiple severe injuries, including a shattered jaw, months of immobilization, and a 13 day coma. His recovery forced him to rebuild his jaw strength from zero and revealed how deeply the jaw affects posture, oral health, proprioception, and cognitive function. Brandon’s experience as a mixed martial artist and his early training of the masseter muscle guided the creation of a safe, medical grade jaw resistance system that now has small clinical data supporting improvements in strength, facial tone, Bruxism relief, and TMJ balance.
You will hear how jaw alignment influences the nervous system, why weak jaws contribute to sleep apnea, how saliva flow ties oral health to gut health, and why resistance training for the jaw produces structural benefits the modern soft diet fails to provide. Host Dave Asprey explains how full range jaw training supports cranial stimulation, nitric oxide signaling, fascia activation, posture correction, and neuromuscular coordination throughout the body. This episode also explores how jaw mechanics connect to biohacking principles like brain optimization, sleep optimization, longevity, neuroplasticity, metabolic signaling, and strength based anti aging.
This is essential listening for anyone focused on biohacking, human performance, posture mechanics, airway stability, TMJ function, oral microbiome health, anti aging, supplements that support structural function, nervous system training, and practical tools that create fast visible results.
You’ll Learn:
Keywords: jaw strength training, TMJ alignment exercise, cranial blood flow stimulation, facial muscle resistance training, bruxism clenching relief, sleep apnea jaw support, oral microbiome improvement, saliva flow activation, jaw posture neuromuscular signaling, masseter hypertrophy training, facial tone anti aging, proprioception jaw connection, airway stability strengthening, hunters gatherers chewing mechanics, tongue plate neck activation, molar alignment biomechanics, jaw range of motion training, piezoelectric bone stimulation, oral health gut health pathway, forward jaw positioning airflow
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Resources:
0:00 – Trailer
A preview of Brandon’s story, his jaw injuries, and how jaw strength affects the entire body.
1:20 – Intro
Host Dave Asprey sets up the episode and introduces Brandon Harris and the origin of Jawzrsize.
2:20 – Brandon’s Accident and Recovery
Brandon describes his shattered jaw, 13 day coma, MMA background, and how months of being wired shut changed his facial strength and cognition.
5:00 – Jawzrsize Origin Story
How Brandon began rebuilding his jaw, the early prototypes, and why facial muscles need structured resistance training.
6:16 – The Science of Jaw Strength
Dave and Brandon break down masseter function, TMJ mechanics, proprioception, cranial nerves, saliva flow, airway position, and why diet affects jaw structure.
17:56 – Clinical Results and User Experience
A review of the small clinical study on jaw strength, wrinkle reduction, facial lift, Bruxism relief, and the rapid visual changes seen with consistent training.
22:48 – Jaw Health, Posture and Systemic Effects
How jaw alignment influences posture, hand eye coordination, sleep apnea, nervous system balance, oral microbiome health, and total body movement patterns.
27:54 – Product Quality and Innovation
Medical grade materials, knockoff concerns, device design, resistance levels, the Jawzrsize app, and upcoming products like mastic gum.
35:59 – Athletic Performance and Neuromuscular Strength
How jaw activation sharpens nervous system firing, improves lifts, enhances proprioception, and benefits athletes across combat sports, racket sports, and endurance.
51:00 – Shark Tank and Brand Journey
Brandon explains the Jazzercise trademark issue, early challenges, and how Jawzrsize became a global facial fitness brand.
52:57 – Final Thoughts and Call to Action
Dave and Brandon recap the core benefits of jaw training and outline how listeners can start integrating it into daily biohacking.
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