Male Hormones: How Testosterone and Toxins Mess With You

Tracy Gapin, M.D.

The current men’s health pandemic has everything to do with hormones and endocrine disruptors. Learn what to balance and clean up.


In this Episode of The Human Upgrade™...

… you’ll learn that while yes, testosterone fuels energy and performance, it’s not the be-all and end-all solution for men’s health woes. A systems biology approach considers many other aspects and provides a broader perspective about what’s going on with you.

This conversation features board-certified urologist Tracy Gapin, M.D., one of the 8th Annual Biohacking Conference keynote speakers. He’ll be on the main stage in Beverly Hills in September. He joins this special preview episode to discuss new ways for men to improve their health and performance. He uses epigenetic coaching, hormones, peptide therapy, biometric monitoring, and unique nutrition and lifestyle interventions.

“Testosterone levels over the last 30 years are down by about 30 percent,” Dr. Tracy says. “Free testosterone, which is the bioavailable, active hormone testosterone is actually down over 45%. This is really important. We’re not just talking about sex and muscle, we’re talking about a man’s life and cardiovascular health and cognitive function. The culprit can be debated, but without question, one of the biggest ones in my mind is endocrine disruptors. Toxins, chemicals in our environment that are clearly crushing men’s health, clearly crushing testosterone. It’s the food we eat, it’s the water we drink, it’s the personal care products. It’s ubiquitous, it’s almost everywhere and it’s getting worse.”

In his book, “Male 2.0™: Cracking the Code to Limitless Health and Vitality,” he says medical school, residency training and even a two-decade career in urology and surgery specialties didn’t teach him how to get to root causes of men’s issues and solve them. He had a health crash of his own at 42. Since neither he nor his doctor had good answers, he went on a quest of discovery and change.

He founded the Gapin Institute for High Performance Medicine and created the proprietary N1 Performance Health Program to go beyond conventional options.

“It's like a symphony. We tend to focus on just one hormone, like testosterone in men, estrogen in women. But it is understanding that it's thyroid, it's cortisol, it's growth hormone, it's vitamin D, it's nitric oxide, it's insulin, it's all these other hormones that get overlooked.”

Tracy Gapin, M.D.

This conversation goes even further into what creates epigenetic signals that affect the function and expression of your genes. You’ll learn, too, that your mindset, stress and environment—and how you do or don’t control those things—have everything to do with your energy and focus.

If you’re aiming for higher performance, Dr. Tracy suggests a trifecta that makes sleep a priority, builds resilience to stress, and creates consistent behaviors with intention.

More about Dr. Tracy Gapin: He’s a member of the American Academy of Anti-Aging, the Age Management Medical Group, and the International Peptide Society. He spent almost 20 years at a urology practice in Sarasota, Fla., where he specialized in robotic surgery, minimally invasive treatment for prostate cancer, and men’s health. He wrote a chapter in the 2020 book, “Codes of Longevity,” as part of 20 contributing experts in the field of aging and longevity. He’s also the co-founder and chief medical officer of Onovi Health, a telemedicine practice specializing in men’s health improvement and performance programs.

SPECIAL OFFER FOR THE HUMAN UPGRADE LISTENERS:  TEXT “HEALTH” to 2 6 7 8 6 to get three bonus gifts.

  1. 10 Secrets To High Performance Health” action steps
  2. A digital copy of the “Male 2.0” book
  3. A link to schedule a call with his team if you want to improve your health and performance   

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  • I spent 20 plus years in traditional medicine and everything changed for me when I developed my own health issues – 3:13
  • We’re going to look at your stool and look at bacteria, look at signs of inflammation, gut health. We’re going to look at blood tests related to organic assets and that’s really the start. Then we do cheek swabs – 9:04
  • Testosterone levels over the last 30 years are down by about 30%. Free testosterone, which is bioavailable, active hormone testosterone is actually down over 45% – 13:37
  • I’ve seen guys that will have a very high total testosterone level. Let’s say it’s 800, 1,000, 1,200, but they’re free is in the tank because their SHBG levels are so high. That’s why it’s so important to check both the free and the total T. – 23:56
  • Bottom line is if you move zinc, copper’s going to move. If you move copper, zinc’s going to move. Move testosterone, estrogen’s going to move. If you understand you’re conducting an orchestra and you can’t just have all tuba all the time, otherwise it’s polka – 27:15
  • If you had to pick three things that the average listener could do that are most likely to improve their hormones, what would it be? – 27:50
  • Male 2.0 was my introduction to a new perspective on men’s health. Male 1.0 is reactive, it’s waiting until you’re sick, it’s waiting until you have symptoms, till you have problems, Male 2.0 is thinking differently. It’s taking a very proactive approach – 31:11
  • When you look at what are the natural ways that you can boost testosterone, it’s sleep, it’s reducing chronically elevated cortisol, it’s insulin sensitivity, it’s strength training. It’s proper healthy nutrition. – 36:44
  • Sleep, stress and consistency are your big three. What does porn do to testosterone? – 42:49

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