EP 1137

1137. Beat Sugar: The Glucose Goddess Method

Biochemist and bestselling author Jessie Inchauspé, aka @GlucoseGoddess, shares her biohacks for managing glucose, the truth behind insulin resistance, and practical tips for a healthier lifestyle.

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In this Episode of The Human Upgrade™...

Blood sugar management as a biohack captures attention for its innovative approach to health. Today’s guest, Jessie Inchauspé, stands out as an expert in guiding practical glucose management, smarter nutritional choices, and unveiling the intricate relationship between diet, blood sugar levels, and overall well-being.

Behind the popular Instagram account @GlucoseGoddess, Jessie educates millions on groundbreaking food habits and has achieved notable success as a French biochemist and New York Times bestselling author, with over a million copies sold of her works, “Glucose Revolution” and “The Glucose Goddess Method,” in 40 languages.

Her unique combination of mathematics and biochemistry expertise opens up the secrets of blood sugar and its significant impact on physical and mental health. The conversation zeroes in on Jessie’s mission to make complex science accessible through simple, transformative tips.

Topics include her groundbreaking research, The Glucose Method study, the launch of her Anti-Spike supplement, and her signature four hacks for glucose management after consuming carbs. The dialogue also covers the benefits of real versus fake sugar, the underlying causes of insulin resistance and diabetes, and how blood sugar spikes influence aging.

This episode unveils Jessie’s remarkable discoveries and biohacks for glucose management, which are crucial for fertility, PCOS, and understanding the health impacts of lifestyle choices like alcohol and nicotine. Jessie’s practical insights offer a path to enjoying favored foods with minimal bodily impact, appealing to both biohacking aficionados and those embarking on a health journey.


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“How do you eat the stuff you love and get all that dopamine from the sweetness with less impact on your body?”



Understanding Glucose’s Role in Our Health

  • What is glucose?
  • Why carbs aren’t a great source of energy 
  • The best way to enjoy sweets
  • Optimal time of day for a cold plunge 
  • Grumpy Old Men (1993)


Enjoying Carbs Without Negative Side Effects

  • How much aging is caused by blood sugar spikes? 
  • Beef vs. chicken: the superior protein choice
  • Jesse’s struggle with mental health after breaking her back
  • Hacks for managing glucose after eating carbs 
  • The different results from taking acetic acid pills vs. drinking vinegar
  • Glucose Goddess Anti-Spike Formula 


The Real Cause of Insulin Resistance & Diabetes 


Addressing Alcohol, Nicotine & The French Paradox


The Glucose Goddess Method Study


Glucose Management for Fertility, PCOS & PMS Cravings

  • Jessie explains how glucose affects fertility 
  • How PCOS is related to spikes in glucose and insulin resistance
  • Unpacking how blood sugar impacts menopause
  • Effects the birth control pill has on your health 
  • How hormonal fluctuations impact your glucose metabolism
  • Tips for controlling your blood sugar if you’re prone to PMS cravings
  • The best thing to eat when you break your fast
  • Why Jesse would rather drink Diet Coke than orange juice


Dave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books 

Website: glucosegoddess.com

Instagram: @glucosegoddess 

Read: Glucose Revolution by Jessie Inchauspé

Read: The Glucose Goddess Method by Jessie Inchauspé

Enjoy the show!


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If you want to lose weight, increase your energy, or sharpen your mind, there are shelves of books offering myriad styles of advice. If you want to build up your strength and cardio fitness, there are plenty of gyms and trainers ready to offer you their guidance. What all of these resources have in common is they offer you a bad deal: a lot of effort for a little payoff. Dave Asprey has found a better way.

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