EPISODE #999

How Urolithin A Helps Create Super T-Cells & Boosts Immunity

Dr. Anurag Singh / Timeline Nutrition

New research and clinical studies connect your mitochondria, immune system and how you age.

Timeline Nutrition sponsored this podcast.
Anurag_Singh_Amazentis

In this Episode of The Human Upgrade™...

… immunologist Anurag Singh, M.D., Ph.D., MBA, Chief Medical Officer at Amazentis, joins the show to talk about urolithin A’s connection between inflammation, aging and your mitochondria.

Urolithin A activates mitophagy and renews your mitochondria.  “It takes all the cellular garbage that has been accumulating over the aging process,” Dr. Singh explains. “It revs it up, so it recharges. And so now, you’re cleaning your metabolic waste products much more efficiently and they become the building blocks. This is mitochondrial biogenesis, and that means newer, healthy mitochondria coming in.”

This new conversation takes an exciting turn into immunity and your immune system’s two lines of defense: innate and adaptive. You’ll learn:

  • how inflammation plus aging (AKA inflammaging) contributes to a weakened immune system and a growing incidence of cancer as you age;
  • how inflammaging and cancer are connected to mitochondrial dysfunction specifically during the aging process; and
  • how to approach your immune health differently with this new knowledge.

A new study recently published in Immunity looks at how immune cells fight cancer better with a focus on immune modulation, immune cell exhaustion and immune responses.

  • The study shows new evidence for the connection between the two known health benefits of Urolithin A: mitophagy activation and immune modulation.
  • The study also points to a close link between mitochondrial health and immune function.

“There's a very close nexus between the mitochondria and the immune system.”

Dr. Anurag Singh / Timeline Nutrition

For more than a decade, Amazentis has focused on how urolithin A could improve healthspan, mostly through muscle health and endurance, and strength. “And over the last five years, we have very quietly also embarked into studying different impacts on immune health and immune metabolism.,” Dr. Singh says. “A lot of urolithin A is anti-inflammatory, but a lot of it is immune modulation. So, it takes a rewiring of the immune system and makes it more conducive to stopping harmful immune responses.”

SPECIAL OFFER FOR THE HUMAN UPGRADE LISTENERS: To learn more about the benefits of urolithin A, go to https://www.timelinenutrition.com and use code UPGRADE10 to get 10% off the plan of your choice.

More about Dr. Anurag Singh: With an M.D. in internal medicine, a Ph.D. in immunology and an MBA, his experience includes work for consumer health and biotech companies. He’s authored more than 30 articles for top science journals, designed and led more than 40 clinical trials, and focused on Urolithin A over the past decade across multiple clinical trials.

Watch this episode on YouTube!

Enjoy the show!

LISTEN: “Follow” or “subscribe” to The Human Upgrade™ with Dave Asprey on your favorite podcast platform.

REVIEW: Go to Apple Podcasts at daveasprey.com/apple and leave a (hopefully) 5-star rating and a creative review.

FEEDBACK: Got a comment, idea or question for the podcast? Submit via this form!

SOCIAL: Follow @thehumanupgradepodcast on Instagram and Facebook.

JOIN: Learn directly from Dave Asprey alongside others in a membership group: ourupgradecollective.com.

  • Our Partners
  • Links & Resources
  • Key Notes

Go Deep on Relaxation & Sleep: https://balooliving.com/dave, use code DAVE for a special discount. Learn more:Put on Some Weight for Better Sleep and Less Stress – Baloo Living – #759

Must-Have Magnesium: https://magbreakthrough.com/dave, use code DAVE10 to get a 10% discount. Learn more: Magnesium: The Master Mineral That Conquers Stress – BiOptimizers – #669

Isometrics for Cardiovascular Health: https://www.zona.com, use code DAVE2022 to get $150 off the Zona Plus. Learn more: Stabilize Your Blood Pressure Using Biofeedback – Mackay Rippey – #853

  • Coming Soon!

Listen and Subscribe using your favorite podcast provider

You may also like

Start hacking your way to better health.

Receive the latest biohacking tips and tech by becoming a Dave Asprey insider.

By sharing your email, you agree to our Terms of Service and Privacy Policy