1310. Top 5 Secret Dopamine Boosters for Superhuman Energy

Brain-Aging Foods Hiding in Your ‘Healthy’ Diet 

Ever wonder why you still feel foggy or forgetful even when you’re eating “clean”? What if the foods you think are good for you are silently aging your brain? As a biohacker who’s spent decades improving my own brain performance, I’ve uncovered a shocking truth: many so-called healthy staples weaken your cognitive function, spike blood sugar, trigger inflammation, and give you massive brain fog. Here are some hidden culprits that could be sabotaging your brain health—and what to eat instead to stay sharp, focused, and vibrant every single day.  

  1. Wheat bread 

Wheat is terrible for your gut. Studies show that gliadin, one of the proteins in wheat, can cause intestinal inflammation and weaken your gut barrier [1]. Because your gut and brain are intimately tied (the gut-brain-axis), when there’s inflammation in your gut, there’s inflammation in your brain. Gluten, the other protein in wheat, is also very hard on your gut. If you’re going to eat bread, use wheat from Europe (their wheat is easier to digest) and ferment it (make sourdough). The fermentation process breaks down wheat proteins, making them easier on your gut. I recommend avoiding wheat whenever you can and instead sticking to low-toxin carbohydrate sources like white rice and low-fructose fruits like blueberries.  

 

2. Industrial seed oils 

Your brain thrives on fat, but the type of fat you eat matters. Studies suggest that the high omega?6 content in many industrial seed oils—like soybean, corn, sunflower, and canola—can promote neuroinflammation and oxidative stress, both of which impair cognitive function [2]. These fats are also highly unstable and extremely processed which means by the time they get to you they’re already rancid. Instead of seed oils, choose stable fats that fuel your brain like butter, ghee, grass-fed beef tallow, MCT oil, coconut oil, and extra virgin olive oil. Read the labels on everything you consume. Food companies sneak seed oils into uncommon foods like mustard, seasonings, or oat milk (see the next point).   

 

3. Oat milk 

Oat milk is a scam. Check the ingredients and you’ll find sugar, water, oats, seed oils, and a bunch of synthetic added vitamins that your body can’t use. Oats are high in phytic acid, which is a plant toxin that binds to minerals and prevents your body from absorbing them. To add to the problem, most oats contain glyphosate. So if you’re drinking oat milk, you’re also getting a meaningful dose of this synthetic pesticide that can cause inflammation in your brain and increase your risk of neurodegenerative diseases like Alzheimer’s disease [3]. If you need to drink milk, a few good options are goat milk, raw, grass-fed A2 cows milk, coconut milk, or macadamia nut milk.  

 

4. Brown rice 

Like oats, brown rice is high in phytic acid. It’s also extremely high in arsenic, which is a harmful heavy metal. Studies show arsenic exposure creates oxidative stress in your brain and can increase your risk of Alzheimer’s disease [4]. 

 

5. Agave syrup 

Agave syrup is around 80% fructose, a type of sugar that your body doesn’t handle well in large amounts. For reference, high fructose corn syrup is around 55% fructose. Studies show that fructose consumption can damage communication between brain cells [5]. Instead of agave syrup, I like to use allulose or small amounts of raw honey or maple syrup.  

 

6. Farmed salmon  

You’ve probably heard that salmon is a brain food but not all salmon is created equal. Compared to wild salmon, farmed salmon contains significantly higher levels of chemicals like polychlorinated biphenyls (PCBs), pesticides, and dioxins. These synthetic chemicals silently weaken your brain. Dioxins are human carcinogens and studies show they can damage your brain and nervous system [6]. To minimize toxin exposure, choose wild-caught seafood. Sockeye salmon is one of the best choices. You’ll still get the beneficial doses of omega-3s without the toxic load.  

 

7. Diet soda 

Diet soda is filled with artificial sweeteners, specifically aspartame. Studies show that long-term aspartame consumption can cause oxidative stress in the brain, impairing memory and cognitive function [7]. Other studies show it can interrupt neurotransmitter balance, potentially contributing to neurological disorders [8]. If you’re going to drink soda, find a brand that uses natural sugar alternatives such as monk fruit or allulose. Or make your own using sparkling water, lemon juice, and allulose.  

 

Your diet plays a powerful role in how your brain ages—and not everything you think is “healthy” is working in your favor. By cutting out these hidden offenders and choosing cleaner, brain-supportive alternatives, you can reduce inflammation, protect your cognitive function, and feel more clear-headed every day. Small changes lead to big results over time. Your brain deserves better fuel—start with what’s on your plate. 

In addition to diet, other brain-supporting tools I use include: BrainTap, Timeline Mitopure supplements and of course, 40 Years of Zen.

Learn more about Neuroscience and habits that effect your brain aging:

 

  1. Lammers KM, Lu R, Brownley J, Lu B, Gerard C, Thomas K, Rallabhandi P, Shea-Donohue T, Tamiz A, Alkan S, Netzel-Arnett S, Antalis T, Vogel SN, Fasano A. Gliadin induces an increase in intestinal permeability and zonulin release by binding to the chemokine receptor CXCR3. Gastroenterology. 2008 Jul;135(1):194-204.e3. doi: 10.1053/j.gastro.2008.03.023. Epub 2008 Mar 21. PMID: 18485912; PMCID: PMC2653457. 
  1. Liu X, Tao R, Guo F, Zhang L, Qu J, Li M, Wu X, Wang X, Zhu Y, Wen L, Wang J. Soybean oil induces neuroinflammatory response through brain-gut axis under high-fat diet. J Tradit Complement Med. 2024 Feb 29;14(5):522-533. doi: 10.1016/j.jtcme.2024.02.002. PMID: 39262663; PMCID: PMC11384091. 
  1. Bartholomew, S.K., Winslow, W., Sharma, R. et al. Glyphosate exposure exacerbates neuroinflammation and Alzheimer’s disease-like pathology despite a 6-month recovery period in mice. J Neuroinflammation 21, 316 (2024). https://doi.org/10.1186/s12974-024-03290-6 
  1. Thakur M, Rachamalla M, Niyogi S, Datusalia AK, Flora SJS. Molecular Mechanism of Arsenic-Induced Neurotoxicity including Neuronal Dysfunctions. Int J Mol Sci. 2021 Sep 17;22(18):10077. doi: 10.3390/ijms221810077. PMID: 34576240; PMCID: PMC8471829. 
  1. Jiménez-Maldonado A, Ying Z, Byun HR, Gomez-Pinilla F. Short-term fructose ingestion affects the brain independently from establishment of metabolic syndrome. Biochim Biophys Acta Mol Basis Dis. 2018 Jan;1864(1):24-33. doi: 10.1016/j.bbadis.2017.10.012. Epub 2017 Oct 7. PMID: 29017895; PMCID: PMC5705281. 
  1. Marinkovi? N, Pašali? D, Feren?ak G, Grškovi? B, Stavljeni? Rukavina A. Dioxins and human toxicity. Arh Hig Rada Toksikol. 2010 Dec;61(4):445-53. doi: 10.2478/10004-1254-61-2010-2024. PMID: 21183436. 
  1. Ashok I, Sheeladevi R, Wankhar D. Acute effect of aspartame-induced oxidative stress in Wistar albino rat brain. J Biomed Res. 2015 Sep;29(5):390-6. doi: 10.7555/JBR.28.20120118. Epub 2014 Jan 12. PMID: 26445572; PMCID: PMC4585433. 
  1. Lindseth GN, Coolahan SE, Petros TV, Lindseth PD. Neurobehavioral effects of aspartame consumption. Res Nurs Health. 2014 Jun;37(3):185-93. doi: 10.1002/nur.21595. Epub 2014 Apr 3. PMID: 24700203; PMCID: PMC5617129. 

 

Unlock Longevity With Your Mitochondria

What if the secret to a longer, healthier life lies within your own cellular power plants? Are you ready to learn about the newest cutting-edge longevity treatment that’s on the horizon as well as ways you can support your longevity right now? The science is rapidly evolving. Let’s dive in. 

Why Mitochondria Matter 

Scientists often dub mitochondria the “powerhouses of the cell,” but they’re far more than just energy producers. Mitochondria are complex, intelligent structures that act as sensors, processors, and even decision-makers in your body. Emerging research shows they may play a key role in emotional regulation, cognitive function, and disease prevention [1][2][3]. The health of your mitochondria determines everything – from how your brain works to how you perform, to whether or not you get a chronic disease. The problem is as you age, your mitochondria start to lose their function.  

The Promise of Mitochondrial Therapeutics aka Mitochondrial Transplantation 

Biotech researchers are working on external bioreactors that can repair and replicate youthful mitochondria. The goal is to reintroduce high-functioning mitochondria into people to restore energy levels, cognitive function, and immune resilience. It’s not science fiction—early animal trials show this can improve cellular energy metabolism, restore mitochondrial function, and prevent cell death [4]. Scientists call this concept mitochondrial transplantation.  

 The Biology Behind the Breakthrough 

Science shows that accumulated damage to mitochondrial DNA is what drives aging [5]. Unlike nuclear DNA, mitochondria replicate quickly and with less quality control, leading to functional decline over time. While stem cell therapies offer some benefits, they don’t come close to what mitochondrial transplantation can do. Mitochondria-based therapy can rejuvenate your body much more – potentially the equivalent of thousands of stem cell treatments. 

Personalized Power 

For now, most research focuses on autologous treatments—repairing and reintroducing someone’s own mitochondria. But in emergencies, or eventually at scale, mass-produced donor mitochondria might become a new category of treatment, like blood transfusions or organ donation.  

And think about the possibilities for biohackers. Your mitochondrial DNA can influence how you process energy, respond to heat, and even resist disease. In the future, you might be able to choose mitochondria based on your geography, athletic goals, or even cognitive needs. 

Applications Beyond Longevity 

Mitochondrial transplantation for longevity and biohacking sounds great, but it also may be the key to treating chronic diseases like Parkinson’s, ALS, glaucoma, and even certain mental health conditions. Many common medications—including antidepressants and statins—may damage mitochondria, so this could reframe how we approach both prevention and treatment. 

6 Ways to Support Your Mitochondria Right Now 

You don’t have to wait for mitochondrial transplantation to start improving your energy and resilience. Here are some practical, science-backed ways to supercharge your mitochondria today: 

        Get Chilly:
        Cold therapy increases a special protein in your body called PGC1- ?. PGC1- ? stimulates your body to create new, healthy          mitochondria [6]. You can do cryotherapy if you’re close to an Upgrade Labs, do a cold plunge at home if you have one, or          simply take a cold shower.  

       Move Daily:
       High-intensity interval training (HIIT) and resistance training activate mitochondrial growth and function [7]. Click here           to learn about how to do the most effective form of high intensity training. 

       Eat (Then Don’t Eat):
       Intermittent fasting improves mitochondrial efficiency and reduces oxidative damage in your cells [8][9] If you’re new to           fasting, go to fastwithdave.com to get started. 

       Sleep Like It’s Your Job:
       Your mitochondria need deep, restorative sleep to repair themselves and regenerate cellular energy [10]. Aim for at least             1.5 hours of deep sleep every night.  

       Ditch Toxins:
       Avoid alcohol, processed seed oils, and endocrine disruptors (like microplastics) that damage mitochondrial membranes           [11]. 

       Get the Right Light:
       Morning sunlight and red and infrared light therapy (660–850nm) directly enhance mitochondrial energy production                 [12]. When you wake up, go outside immediately and get 5-10 minutes of sunlight on your bare skin. 

A Bold Vision for the Future 

Imagine a world where we test mitochondrial health as routinely as cholesterol. And then if something is wrong, imagine being able to fix it with cutting edge treatments like mitochondrial transplantation. Emerging mitochondrial therapies are going to transform how you age, perform, and heal. Get ready! 

Dave’s Pick: Upgrade Your Mitochondria Today 

You don’t have to wait for mitochondrial transplants to boost your energy and longevity. I use Timeline’s Mitopure—a breakthrough form of Urolithin A that clears out weak mitochondria and builds stronger ones. 

It’s like a cellular reboot. 

Watch the full YouTube video on How to Help Your Mitochondria:

References 

  1. Giménez-Palomo A, Dodd S, Anmella G, Carvalho AF, Scaini G, Quevedo J, Pacchiarotti I, Vieta E, Berk M. The Role of Mitochondria in Mood Disorders: From Physiology to Pathophysiology and to Treatment. Front Psychiatry. 2021 Jul 6;12:546801. doi: 10.3389/fpsyt.2021.546801. PMID: 34295268; PMCID: PMC8291901. 
  1. Picard M, McEwen BS. Mitochondria impact brain function and cognition. Proc Natl Acad Sci U S A. 2014 Jan 7;111(1):7-8. doi: 10.1073/pnas.1321881111. Epub 2013 Dec 23. PMID: 24367081; PMCID: PMC3890847. 
  1. San-Millán I. The Key Role of Mitochondrial Function in Health and Disease. Antioxidants (Basel). 2023 Mar 23;12(4):782. doi: 10.3390/antiox12040782. PMID: 37107158; PMCID: PMC10135185. 
  1. Kim JS, Lee S, Kim WK, Han BS. Mitochondrial transplantation: an overview of a promising therapeutic approach. BMB Rep. 2023 Sep;56(9):488-495. doi: 10.5483/BMBRep.2023-0098. PMID: 37679296; PMCID: PMC10547968. 
  1. Somasundaram I, Jain SM, Blot-Chabaud M, Pathak S, Banerjee A, Rawat S, Sharma NR, Duttaroy AK. Mitochondrial dysfunction and its association with age-related disorders. Front Physiol. 2024 Jul 2;15:1384966. doi: 10.3389/fphys.2024.1384966. PMID: 39015222; PMCID: PMC11250148. 
  1. Halling JF, Pilegaard H. PGC-1?-mediated regulation of mitochondrial function and physiological implications. Appl Physiol Nutr Metab. 2020 Sep;45(9):927-936. doi: 10.1139/apnm-2020-0005. Epub 2020 Jun 9. PMID: 32516539. 
  1. Mahatme S, K V, Kumar N, Rao V, Kovela RK, Sinha MK. Impact of high-intensity interval training on cardio-metabolic health outcomes and mitochondrial function in older adults: a review. Med Pharm Rep. 2022 Apr;95(2):115-130. doi: 10.15386/mpr-2201. Epub 2022 Apr 28. PMID: 35721039; PMCID: PMC9176307. 
  1. Mehrabani S, Bagherniya M, Askari G, Read MI, Sahebkar A. The effect of fasting or calorie restriction on mitophagy induction: a literature review. J Cachexia Sarcopenia Muscle. 2020 Dec;11(6):1447-1458. doi: 10.1002/jcsm.12611. Epub 2020 Aug 27. PMID: 32856431; PMCID: PMC7749612. 
  1. Hardiany NS, Karman AP, Calista ASP, Anindyanari BG, Rahardjo DE, Novira PR, Taufiq RR, Imtiyaz S, Antarianto RD. The Effect of Fasting on Oxidative Stress in the Vital Organs of New Zealand White Rabbit. Rep Biochem Mol Biol. 2022 Jul;11(2):190-199. doi: 10.52547/rbmb.11.2.190. PMID: 36164627; PMCID: PMC9455196. 
  1. Richardson RB, Mailloux RJ. Mitochondria Need Their Sleep: Redox, Bioenergetics, and Temperature Regulation of Circadian Rhythms and the Role of Cysteine-Mediated Redox Signaling, Uncoupling Proteins, and Substrate Cycles. Antioxidants (Basel). 2023 Mar 9;12(3):674. doi: 10.3390/antiox12030674. PMID: 36978924; PMCID: PMC10045244. 
  1. Reddam A, McLarnan S, Kupsco A. Environmental Chemical Exposures and Mitochondrial Dysfunction: a Review of Recent Literature. Curr Environ Health Rep. 2022 Dec;9(4):631-649. doi: 10.1007/s40572-022-00371-7. Epub 2022 Jul 28. PMID: 35902457; PMCID: PMC9729331. 
  1. Jeffery G, Fosbury R, Barrett E, Hogg C, Carmona MR, Powner MB. Longer wavelengths in sunlight pass through the human body and have a systemic impact which improves vision. Sci Rep. 2025 Jul 8;15(1):24435. doi: 10.1038/s41598-025-09785-3. PMID: 40628952; PMCID: PMC12238558. 

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