Could Understanding Your Gut Microbiome Help Reverse Autoimmune Disease?

Could Understanding Your Gut Microbiome Help Reverse Autoimmune Disease?

Your gut microbiome is more than a collection of bacteria. It’s a complex ecosystem of around 100 trillion microbes that can include bacteria, archaea, viruses like bacteriophages, yeast and fungi, as well as parasites. It helps to think of this ecosystem of microbes more like an organ. In fact, your gut microbiome weighs between four and five pounds, making it heavier than your brain.

Your gut is home to the majority of your immune system, around 70 to 80% of all immune system cells. So it’s not surprising that this ecosystem plays a huge role in the development of autoimmune disease. Read on to learn more about the link between an imbalanced gut and autoimmune issues, and the best ways to heal your gut microbiome.

Leaky gut and autoimmune disease

Think of the gut microbial ecosystem as a rainforest, in that it thrives when there is high biodiversity. Unfortunately, antibiotics, toxins, a diet high in processed foods, and the overall Western way of life have contributed to a significant loss in diversity, stability, adaptability, and resilience of the gut microbiome. That’s a problem, and here’s why: A gut microbiome imbalance (dysbiosis) contributes to leaky gut syndrome and immune system dysregulation – which can lead to autoimmune disease.

The leaky gut and autoimmune connection is more than an association – these two conditions lie on a spectrum. As the leakiness of your gut worsens, you’re more and more likely to develop an autoimmune disease. On the opposite end, when you take steps to repair your gut lining, you move towards reversing autoimmunity.

How to tell if you have a leaky gut

If you have an autoimmune condition, it is likely that you have a leaky gut. Here are the 9 signs you have a leaky gut:

  • Chronic or recurring digestive issues: These can range from mild gas, bloating, diarrhea or constipation to debilitating irritable bowel syndrome and more.
  • Food sensitivities or allergies: When a patient comes into my office with a food sensitivity, this tells me they likely have a leaky gut. The more sensitivities they have, the leakier their gut is likely to be.
  • Brain fog: Difficulty thinking, concentrating or even ADD (attention-deficit disorder).
  • Mood-related issues: Leaky gut often contributes to anxiety and depression.
  • Skin conditions: Rosacea, eczema, dandruff, acne, and psoriasis are all associated with leaky gut.
  • Seasonal allergies: Allergies and asthma are other common signs of leaky gut.
  • Hormonal imbalances: Irregular periods and hormone-related conditions are exacerbated by leaky gut.
  • Autoimmune disease: Leaky gut leads to autoimmunity. So if you’ve received an official diagnosis, it’s time to work on healing your gut.
  • Chronic fatigue: Gut issues can contribute to extreme fatigue and related diagnoses like fibromyalgia.

If you experience one or more of the symptoms above, you’ll want to take steps towards healing your gut.

As mentioned, leaky gut and autoimmune disease lie on a spectrum. As your gut health degrades and you develop symptoms, it becomes more and more likely your immune system will be sent into hyperdrive – eventually resulting in an autoimmune disease.  

Optimizing gut intelligence could help you heal faster

To repair your gut you want to:

  1. Remove damaging elements.
  2. Restore essential ingredients that might be missing.
  3. Reinoculate beneficial bacteria and other microbes.
  4. Repair by providing nutrients that help to repair the lining of the gut.

Your gut microbiome is completely unique. What if you had a way to see into your gut and identify even more closely the specifics of your gut microbiome composition and activity, so you could further individualize food and nutrient recommendations?

That’s where a gut test comes in.

Viome’s testing uses metatranscriptomic sequencing of the gut microbiome. That simply means it can identify all your active microbes down to the strain level, and understand exactly what each of your microbes is doing, eating, producing, and how they are interacting with each other. Through an expert trained AI analysis engine, Viome is able to give personalized dietary and nutrient recommendations that will help to balance your unique microbiome.

Learn more about Viome’s Gut Intelligence Test

Find the perfect diet to heal your gut

Reversing your autoimmune condition starts with your diet, and eating the foods that are right for you. You begin that process by eliminating inflammatory foods — the foods that cause your immune system to go into overdrive.  

Gluten and dairy are major culprits behind leaky gut and autoimmunity, but there may be other problematic foods that are exacerbating the issue, including so-called “health” foods.

For example, a food component called oxalates are common in foods like spinach, chard, kale, nuts, seeds, and cocoa. Viome has identified that about 40% of their customers’ microbiomes are not able to metabolize oxalates in a way that neutralizes their damaging effects. Ingesting oxalate-rich foods without having the bacteria that can properly metabolize them can cause big problems, especially if you already have a leaky gut.

But how do you know if you belong to the 40% of people who should eat fewer oxalate-containing foods? Viome’s testing can provide you with that information.

When you minimize problematic foods, you significantly reduce the wear and tear on your gut. It’s like pulling back the troops and giving your gastrointestinal lining a chance to recover and regroup – and it’s an essential step in reversing autoimmune disease.

Viome recommends food for better inoculation

This is one of the most fascinating aspects of Viome testing. With today’s probiotics we only have access to maybe 30 or so different strains of bacteria – but your gut contains hundreds of different strains of bacteria, not to mention all the viruses, fungi, and more, meaning available probiotics are barely making a dent in the biodiversity that should be there.

High levels of biodiversity make a stronger gut microbiome, which in turn supports a stronger immune system – but we are limited by what’s available on the market.

Viome testing, analysis, and recommendations specifically tell you what to eat in order to manipulate the microbe activity in your gut. This tips the scales in your favor. Not only do you get targeted nutrition advice that tells you exactly what to eat to optimize your gut – you also learn what is going to feed beneficial microbes, while reducing harmful ones.

Your microbes are like picky children — they only like certain foods. When you get your Viome results back, the recommendations tell you which foods you should eat to support the best microbes for your health and wellness.

Improving gut health from multiple angles

Viome is a new technology that was originally created for biodefense purposes. When you’re working on reversing autoimmune disease, add Viome to your biohacking arsenal. Knowing what’s going on in your gut is the first step to healing it.

Order your Viome Gut Intelligence Test now for only $149 

 

Study Shows Pregnant Women are the Ultimate Endurance Athletes

A new study spells out what women have suspected for generations: pregnancy is the toughest endurance event your body can do.[ref url=”https://advances.sciencemag.org/content/5/6/eaaw0341″]

Cue the not-so-surprised gasps from mothers across the globe…

Pregnancy puts the same demands on your body as extreme multi-month endurance races do. The research team measured the oxygen and nutrient expenditure during a range of activities that use different muscle groups and organ systems, including ultra-running, swimming, cycling, trekking, and pregnancy. They found that these activities followed the same sustained expenditure curve, which graphs athlete’s and mothers’ energy usage while performing in their respective athletic events.

The study authors left out a key detail (not by oversight — it wasn’t the focus of the study). Pregnancy culminates with birth, which amounts to a few hours to several days of high-intensity interval training with the potential for tissue damage here and there. Imagine doing the Race Across America, a 3000-mile bike race spanning 12 states, then ending with a full day of Crossfit (no breaks!) that may or may not result in stitches.

Then there’s the recovery period. Once the athletic event comes to an end, someone wakes you up from your sleep every two hours and skims off the top of your energy and nutrient stores that would otherwise be put toward recovery.

You guys, women are fierce.

Think about it. When you’re pregnant, you’re a bodybuilder. While you’re going about your life, your body is busy stitching together a pair of lungs, linking all of the parts of baby’s digestive system, assembling a full skeleton, and so much more.

How to meet your body’s energy demands during pregnancy

You can talk to your OB/GYN about what to eat and how much to eat during pregnancy. Here are some ways to meet your body’s increased requirements while you’re growing a human.

Eat high-quality fats

Gram for gram, fat provides your body with more than twice the energy that carbohydrates provide. Not only that, but your brain and your baby’s brain is made up of over 60% fat.

Here’s how to choose the right fat.

Load up on deeply colored vegetables

Brightly colored vegetables are rich in nutrients for you and your baby. They also contain polyphenols, which are antioxidant compounds that nourish and protect your cells and your baby’s developing cells and tissues.

Here’s a recipe for quick pickled vegetables. Make a big batch this weekend and you’ll have them on hand whenever you need some extra veg on your plate. Also: they’re pickles.

Breathe

During pregnancy, your oxygen demand goes up right along with your energy demand. A few deep breaths several times per day can give your cells the quick burst of oxygen they need. Here is an easy, stress-relieving box breathing exercise that you can practice today, and then it’s there for you whenever you need it.

Hug your mom and the mother of your children today. They’re the strongest people you know.

 

13 Bulletproof-Approved Items and Foods to Buy at Target

You know how it goes: You walk into Target with the goal of buying one, maybe two, items, and an hour later you’ve left with an entire shopping cart of things. The phenomenon is known as the “Target Effect,” and it’s no wonder people can’t get enough of the big-box retailer. It sells just about everything, including products for the aspiring biohacker. Read on for the best Bulletproof-approved items and foods to buy the next time you head to the store.

Blue Hill Bay Smoked Wild Alaskan Sockeye Salmon, $6.99 for 3oz.

Choose wild-caught salmon over farm-raised; it’s better for your health, and for the environment. Wrap a slice around a creamy chunk of avocado as a snack, or add to a salad for a healthy dose of omega-3s. Smoked salmon brands typically contain sugar, but this Blue Hill version is unsweetened, giving it the Bulletproof thumbs up.

Bulletproof Cold Brew, 4-pack

Only available in-store at Target; prices may vary

For busy mornings, grab a Bulletproof Cold Brew. Each bottle contains high-quality coffee, Brain Octane oil, and grass-fed butter. The caffeine mixed with powerful fats gives you focus, banishes cravings, and burns fat, helping you power through your day. Cold Brew comes in a variety of flavors — vanilla, mocha, and original. For an extra creamy taste, try Cold Brew with Collagen Protein.

Organic avocados, $4.99 for a 4ct. bag

Bulletproof is all about avocados. This creamy, high-fat fruit fights inflammation and lowers blood pressure. It’s also approved on keto, paleo, and Whole30 meal plans. Get inspired with these 30 delicious and easy avocado recipes.

Thank you cards

Prices vary

Gratitude rewires your brain. Saying thanks builds lasting neural plasticity to more positive thinking. There are different ways to show gratitude — writing down what you’re grateful for each day is one option. Another is to write a note or a letter to someone who has touched your life. That can be a friend, a family member, a teacher, or an acquaintance — anyone who has helped shape you. Target sells a wide variety of beautifully-designed thank you cards at affordable prices.

Bulletproof Brain Octane GoPacks

Only available in-store at Target; prices may vary

Brain Octane oil is a purified form of saturated acids called medium-chain triglycerides (MCTs). There are different types of MCTs, and some of these convert to ketones more quickly than others. Brain Octane is pure C8, the most ketogenic oil. Throw these convenient single-serve to-go packs in your gym bag for pre-workout fuel, or pack them in your suitcase when you travel.

Organic blueberries

Prices vary

Blueberries fall in the green zone on the Bulletproof Diet. They’re nutrient-dense and full of anti-inflammatory polyphenols. They make a great dessert on their own, or toss them in a salad for a little zing.  

Contigo Stainless Steel Travel Mug, $19.99

What to do when you don’t have time to sip your Bulletproof Coffee at a leisurely pace at home? Pour it into a Contigo travel mug and head out the door. The sealed lid is leak and spill proof and drinks stay hot for up to five hours.

Green Giant Riced Veggies (frozen), starts at $2.69

Dinners are a cinch with these frozen riced veggies from Green Giant. Choose between butternut squash, broccoli, cauliflower, and veggie combos, like the cauliflower and sweet potato. Going low-carb has never been this easy.

Bulletproof Unflavored Collagen Protein

Only available in-store at Target; prices may vary

Collagen protein (also known as collagen peptides and hydrolyzed collagen) can plump your skin and support your joints. It’s no surprise Hollywood stars and influencers are pouring it into their coffee and smoothies. Just two scoops a day can reverse the clock on aging.

Kerrygold Irish Butter

Prices vary

Organic, grass-fed butter is one part of the holy trifecta of Bulletproof Coffee (along with high-quality coffee beans and Brain Octane oil). This healthy fat is jam-packed with omega-3 fatty acids, antioxidants, and vitamins. Add it to your coffee or use it to make this 3-ingredient keto avocado butter.

Unsalted Raw Almonds, $13.49 for 32 oz.

A handful of raw almonds make a great snack to tide you over until dinner. Keep in mind that nuts can be high in mold toxins and spoil easily. Store them in the fridge to extend their shelf life.   

Bodum Schiuma Milk Frother, $9.99

A simple milk frother is a quick and easy-to-clean option to blend your Bulletproof Coffee in the morning. It’s also a lot more affordable than a high-powered blender. To avoid spills or splashes, froth your coffee in a mason jar or ceramic pitcher, then pour into a mug.

Epsom Salt Fresh Bath Soak, $4.99 for 8 lbs.

The majority of people are deficient in magnesium, which can lead to fatigue, anxiety, and aches and pains, to name a few symptoms. One way to up your levels is to take a bath with epsom salts, which are magnesium sulfate crystals. This form of magnesium absorbs through the skin. Pour 1-2 cups of epsom salts in your bath twice a week to feel the benefits.  

Read next: 12 Best Paleo Foods You Can Find at Walmart 

 

Over-the-Counter Pain Reliever Reduces Your Empathy, and Other Reasons to Avoid Taking It

[tldr]

  • It’s a common misconception that if a medicine is available without a prescription, it’s not that strong or risky.
  • Studies in the last few years show that the popular over-the-counter pain reliever acetaminophen (leading brand Tylenol) dulls not only your physical pain, but also dulls your emotional connection with others.
  • The medical community is well aware of liver problems, even liver problems that lead to death, from acetaminophen.
  • Here’s what to use instead, and what to do to protect yourself if there’s no way around taking it.

[/tldr]

It’s a common misconception that if a medicine is available without a prescription, it’s not that strong or risky. That couldn’t be further from the truth. The most popular pain reliever and fever reducer, acetaminophen, affects your liver and even reduces your ability to emotionally connect with others.

Keep reading to find out why acetaminophen is a powerful and potentially dangerous drug that comes with plenty of risks, what to take instead, and how to protect yourself if you absolutely must have acetaminophen.

Acetaminophen and empathy

A handful of studies in the last few years show that the popular over-the-counter pain reliever acetaminophen (leading brand Tylenol) dulls not only your physical pain, but also dulls your emotional connection with others.

One study showed that acetaminophen reduced empathy in rats,[ref url=”https://www.sciencedirect.com/science/article/pii/S0091305718304258″]
and a human study showed that it reduced positive empathy, which is the happiness you feel when something good happens to someone else.[ref url=”https://philpapers.org/rec/MISASA”] Another human study showed that acetaminophen reduced trusting behaviors in others.[ref url=”https://www.nature.com/articles/s41598-019-40093-9″] Empathy and relationships are a huge part of being human, and it’s alarming to think that a common medicine that people take for a headache essentially takes away a part of your soul.

Scientists have identified that chronic acetaminophen use changes serotonin receptors and depletes serotonin itself.[ref url=”https://www.sciencedirect.com/science/article/abs/pii/S0197018699000236″][ref url=”https://physoc.onlinelibrary.wiley.com/doi/pdf/10.1016/j.clpt.2005.12.307″][ref url=”https://www.painphysicianjournal.com/current/pdf?article=MTE4NA%3D%3D&journal=47″] Since serotonin is a major player in happiness and empathy,[ref url=”https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2951404/”] not having enough could be causing hiccups in your ability to connect with people.

Acetaminophen and liver toxicity

Human connection isn’t the only reason to break up with acetaminophen. The medical community is well aware of liver problems, even liver problems that lead to death, from acetaminophen.[ref url=”https://livertox.nih.gov/Acetaminophen.htm”]

Liver problems from acetaminophen aren’t just from overdosing. Researchers found higher toxicity and death from people who used acetaminophen over a long period, as compared to people who took mega-doses of acetaminophen to harm themselves.[ref url=”https://www.ncbi.nlm.nih.gov/pubmed/9329933?dopt=Abstract”] This is likely because patients who overdosed got immediate medical attention, while long-term misuse of compounded negative effects over the long term without taking measures to counteract it.

Acetaminophen depletes glutathione in your liver, which is known as the “master antioxidant” that your body makes on board. You’re more susceptible to liver injury by acetaminophen if you drink alcohol frequently.[ref url=”https://www.ncbi.nlm.nih.gov/pubmed/7657281?dopt=Abstract”][ref url=”https://www.ncbi.nlm.nih.gov/pubmed/3553308?dopt=Abstract”][ref url=”https://www.ncbi.nlm.nih.gov/pubmed/7990219?dopt=Abstract”] Alcohol depletes your glutathione, and if you’re taking acetaminophen on top of that, you’re tanking your levels to dangerous lows.

Your body uses glutathione to protect your brain, your heart, your eyes, and more. Here’s a complete guide to glutathione and why you want to keep your levels up.

What to take instead of acetaminophen

melatonin sleep supplementsEven when you’re Bulletproof, you’ll still run into instances when you need a pain reliever. Here’s are some things to try before you reach for over-the-counter meds.

Curcumin or turmeric

Curcumin is the active compound in bright-yellow turmeric root. Studies show that curcumin blocks the production of inflammatory cells[ref url=”https://www.ncbi.nlm.nih.gov/pubmed/21804201″] which can help cut down on pain. You can read more about curcumin here.

RELATED: Natural Pain Relief Methods that Work

White willow bark

White willow bark has been used traditionally as a pain reliever, then fell out of practice when pharmaceutical companies started making pain medicines instead. You can’t patent a plant, so the earliest chemists made synthetic versions of the active compounds in medicinal plants, in order to profit from them. Back in the 1800s, the chemist who founded Bayer invented aspirin by creating a synthetic form of salicin, the active compound in white willow bark.

Liquid naproxen

If you absolutely have to have a pain reliever, liquid naproxen is the easiest one for your body to bounce back from. Work with a doctor when you use it, and keep it short-term.

What to do when you absolutely have to take acetaminophen

scarlet feverThere are rare instances when your doctor will tell you that there’s no way around taking acetaminophen. That doesn’t mean your liver, serotonin, and empathy are doomed — but protecting yourself is crucial while you’re taking it. Here’s what to do.

Vitamin C

If you have an illness or injury that requires acetaminophen, your body probably needs extra vitamin C anyway. Vitamin C, like glutathione, can protect all of your cells, including liver cells, from oxidative damage during times of high stress and infection.

Glutathione

Acetaminophen depletes glutathione, so most functional medicine doctors will increase your glutathione stores before treatment and support your body’s ability to make glutathione during the course of treatment. They do this by having patients take n-acetylcysteine (NAC) or a liposomal glutathione supplement before and during treatment with acetaminophen.

In one study, researchers found that NAC didn’t increase glutathione but it did increase the liver’s ability to make glutathione when the demand increased like it does when you take acetaminophen.[ref url=”https://link.springer.com/article/10.1007/BF00609183″]

Curcumin

Research shows that curcumin protects against acetaminophen-induced liver and kidney damage in rats, and that using curcumin along with glutathione had a synergistic protective effect.[ref url=”https://www.sciencedirect.com/science/article/pii/S0014299909010425″] That means, the effects of both together were larger than the combined effects of both used separately.

Milk thistle

Milk thistle is a plant with an active compound called silymarin that has been shown to protect the liver against oxidative stress.[ref url=”https://onlinelibrary.wiley.com/doi/full/10.1111/jvim.12002″][ref url=”http://nopr.niscair.res.in/handle/123456789/3404″]

After acetaminophen

A case study showed that after stopping acetaminophen, your liver function returns to normal.[ref url=”https://annals.org/aim/article-abstract/691410/chronic-liver-disease-acetaminophen”] Glutathione and things that help your body make glutathione would help get your glutathione stores back up and speed up that process.

 

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