1341. Rollin McCraty: Master Stress in 10 Seconds with This Heartbeat Technique

Ketones: The Brain-Boosting Fuel That Burns Clean

You’ve been told that sugar is energy.
It’s not the best energy.

Your brain and mitochondria were built to run on ketones – the clean, efficient fuel your body makes from fat. Once you know how to tap into ketones strategically, you can boost focus, energy, and fat-burning without starving yourself or wrecking your hormones.


What Are Ketones?

Ketones are molecules your liver produces when it breaks down fat for energy. When you lower carbs or fast, your body naturally makes ?-hydroxybutyrate (BHB), acetoacetate (AcAc), and acetone—collectively known as ketone bodies.

Unlike glucose, ketones don’t spike your blood sugar or insulin. They fuel your brain, heart, and muscles more efficiently and with fewer free radicals.

In a landmark study, Oxford University researchers found that ketone metabolism produces ~28% more energy per unit of oxygen than glucose does (Cox et al., Cell Metabolism, 2016). Translation: more power, less cellular “exhaust.”


Why Your Brain Loves Ketones

Your brain can’t burn fat directly – but it can burn ketones. In fact, it prefers them. Research shows neurons generate more ATP and less oxidative stress when running on ketones instead of glucose (Morris, Neurochemistry International, 2005).

Ketones also reduce inflammation in brain cells (Kashiwaya et al., PNAS, 2000), which supports sharper cognition, steadier mood, and improved resilience under stress.

If you’ve ever noticed laser-focus after a cup of Danger Coffee with MCT Oil, that’s because your body is quickly converting C8 MCT into ketones within minutes.


The Anti-Inflammatory Edge

Ketones don’t just provide fuel – they signal your cells to perform better.
-hydroxybutyrate inhibits the NLRP3 inflammasome, a key driver of chronic inflammation (Youm et al., Nature Medicine, 2015).

Less inflammation? Better mitochondrial efficiency? Slower aging.
That’s one of the reasons why nutritional ketosis is being explored for neurodegenerative and metabolic conditions.


Control Hunger, Not Willpower

Ketones help you go longer without crashing or craving junk. They lower ghrelin, your hunger hormone, leading to steadier appetite and better metabolic control (Stubbs et al., Obesity, 2018).

That’s why you can power through a morning in mild ketosis without feeling hangry – or why fasting suddenly feels effortless once your mitochondria switch over.


Endogenous vs. Exogenous Ketones

You can either make ketones (endogenous) or drink them (exogenous). Both have benefits:

  • Endogenous ketones: Produced during fasting or a low-carb, high-fat diet.
  • Exogenous ketones: Supplements that raise blood ketones quickly, even without fasting.

The two main forms are:

  1. Ketone salts – BHB bound to minerals like sodium or magnesium. Easier on taste, moderate effect.
  2. Ketone esters – BHB bound to an alcohol molecule (like 1,3-butanediol). Stronger, cleaner, but less tasty and more expensive.

In a placebo-controlled study, ketone esters improved endurance and cognitive performance under stress (Holdsworth et al., Frontiers in Physiology, 2017).

If you want that fast-acting ketone boost, try Ketone-IQ™—it’s the same formula I use on long flights and deep-work days.


Mitochondrial Upgrade Mode

Ketones are a mitochondrial performance enhancer. They increase the NAD/NADH ratio, reduce oxidative stress, and upregulate genes for longevity (Veech et al., Prostaglandins, Leukotrienes & Essential Fatty Acids, 2014).

More NAD? = better repair, stronger energy production, and slower cellular aging.

That’s why biohackers often describe being in ketosis as “calm energy.” You’re producing energy cleanly instead of fighting inflammation from sugar spikes.


How to Use Ketones Strategically

You don’t have to live in ketosis 24/7. The smarter approach is metabolic flexibility – training your body to switch fuels efficiently.

Here’s a sample structure based on biohacker best practices:

Morning:

  • Drink Danger Coffee® blended with MCT Oil (C8 MCT) to raise ketones fast.

Mid-morning:

  • Measure blood BHB (0.5–1.0 mmol/L = optimal focus range) using AXO Labs.

Pre-workout or heavy cognitive load:

Evening:

  • Once or twice per week, add a carb refeed (white rice or sweet potato) to keep thyroid and hormones balanced.

The goal: Teach your mitochondria to burn both fat and carbs—without the metabolic “lag.”


Benefits You’ll Notice

  • Sharper mental focus and clarity
  • More stable energy and mood
  • Better fat metabolism
  • Lower inflammation
  • Deeper sleep and recovery
  • Improved endurance and resilience

It’s not just about losing fat – it’s about running your body on a higher-octane fuel.


Key Research


Final Takeaway

Ketones are the ultimate clean-burning fuel.
They stabilize your energy, sharpen your focus, and optimize your metabolism at the cellular level.

Start small. Add MCT Oil to your morning coffee. Try Ketone-IQ™ before a demanding day or flight. Experiment with fasting or carb cycling to discover your metabolic sweet spot.

When your mitochondria run on ketones, you don’t just feel better – you perform younger.


Watch: Ketones & Brain Health

Shop Biohacker Essentials:

Affiliate Disclosure: Some links may earn commissions that support educational content and ongoing biohacking research.

 

Salt Re-Examined: Why Your Cells Actually Need It for Hydration, Energy & Performance

We’ve heard for decades: “Cut the salt.” But what if the real story isn’t simply “less salt,” but which salt, how much, and when? I dig into the true role of salt—how your body uses sodium and chloride, why athletes and biohackers often need more than the average person, and how choosing the right type of salt can improve hydration, focus, and performance.


What Salt Actually Does

Salt (primarily sodium chloride) does far more than season food. It plays a pivotal role in fluid balance, nerve signaling, muscle contraction, and maintaining the electrical voltage across your cells.
When you allow sodium levels to drop—either through excessive sweating, low-carb diets, frequent sauna sessions, or over-hydration—you reduce your cells’ voltage and impair performance.
In one study, exercise in heat coupled with low sodium intake led to significantly increased risk of low blood-sodium states. (PMC)
In another large analysis, small changes in dietary salt intake altered plasma sodium and extracellular fluid volume, which affects cellular function. (American Heart Association Journals)

This means: drinking water helps—but if you’re not supporting sodium and chloride, your hydration may stay superficial. Your body might be hydrated externally, but your cells remain under-charged.


Why “Low Salt” Settings Can Hurt Performance

If you train intensely, fast, expose yourself to heat or sauna, or follow a low?carbohydrate diet, you’re likely flushing a lot of sodium. Without replacing it:

  • Blood volume may decline ? less oxygen and nutrient delivery.
  • Nervous system signaling slows ? muscle performance drops.
  • You may crave salt or feel sluggish and light-headed.

For example, a hydration study found that fluids with added sodium improved hydration and plasma volume recovery better than plain water after heavy exercise. (Cadence™)
Also, a recent intervention found replacing part of salt with a potassium salt had direct effects on cardiovascular outcomes—showing that the type and balance of salt matter too. (American Heart Association Journals)

So if you’re living a performance or fasting lifestyle, seeing your salt intake as a variable—not just a fixed background number—is smart.


Real Salt vs. Table Salt

Not all salts deliver equal benefit. Here’s what to look for:

  • Refined table salt often contains mostly sodium chloride, with anti-caking agents, and lacks trace minerals. Over-reliance on it might disturb the electrolyte balance.
  • Unrefined or mineral-rich salts, like those harvested from ancient seas or deserts, provide sodium with supporting trace minerals (magnesium, potassium, etc.) that assist cellular hydration and signaling.
  • That’s why I prefer the Oryx Desert Salt—as part of my stack I use when performance, travel or recovery demand premium support.
    Try Oryx Desert Salt here (affiliate link).

When you upgrade which salt you use—not just the amount—you upgrade the downstream effect on your hydration, energy and cellular voltage.


How to Use Salt Smartly

Here’s how I integrate salt into my routine (active lifestyle, travel, training) and how you can too:

  • On training or sauna days: Add ½ to 1 teaspoon of high-quality salt (like Oryx) into your water or beverage after heavy sweat.
  • During fasting or low?carb days: When insulin falls, kidneys excrete more sodium—so proactively add salt to prevent drop in energy and focus.
  • With travel and time-zone shifts: Salt helps maintain fluid volume, prevent dehydration and support focus when your rhythm is off.
  • Avoid over-doing it: If you have hypertension, kidney disease or are on sodium?restricted diets, you must consult your physician.

Myths & Reality

Myth: “All salt is bad for you.”
Reality: For many healthy, active adults, the right salt in the right context supports hydration and performance—not just cardiovascular risk.

Myth: “You don’t need salt if you drink enough water.”
Reality: Water without sodium can fail to properly hydrate at the cellular level. When plasma sodium drops, your cells lose voltage even though you’re “hydrated.”

Myth: “Salt automatically raises blood pressure.”
Reality: The relationship is more complex—diet quality, activity level, genetics and mineral balance all matter. Some trials show modest sodium changes impact blood pressure; others show context is key. (Harvard Health)


Watch: Salt & Your Family

In this YouTube episode, I walk through:

  • Why salt matters for cellular voltage and hydration
  • The difference between types of salt
  • My actual protocol: how much, when, and how I use it

Watch now: Should You Give Babies Salt?


Bottom Line

Salt isn’t the villain—it’s how and which salt you use that determines the outcome.
Use high-quality salt, pay attention to your context (training, fasting, sweating, travel), and you’ll unlock hydration, performance, and cellular health you didn’t even know was missing.
It’s time to look at salt not just as seasoning—but as foundational to your biology and performance.

 

Start hacking your way to better than standard performance and results.

Receive weekly biohacking tips and tech by becoming a Dave Asprey insider.

By sharing your email, you agree to our Terms of Service and Privacy Policy