The Rock Star Scientist of Alzheimer’s on How to Stop Neuroinflammation – Dr. Rudolph Tanzi with Dave Asprey – #707

June 3, 2020 by Dave Asprey

In this episode of Bulletproof Radio, we’re honoring Alzheimer’s and Brain Awareness Month with Dr. Rudolph Tanzi. He’s a renowned microbiologist who has researched, studied, and written about Alzheimer’s disease for nearly 40 years. Along the way, he’s discovered several Alzheimer’s disease genes, including all three early-onset familial Alzheimer’s genes.

He’s also developing therapies for treating and preventing Alzheimer’s disease using human mini-brain organoid models of the disease and working to identify novel genes associated with Alzheimer’s and autism spectrum disorders.

“You’re trying to put out a forest fire by blowing out the match,” Dr. Tanzi says. “The forest fire’s neuroinflammation. These early genes taught us about the triggers, the matches, the brush fires. It’s too late to stamp those out. But now, all the newest Alzheimer’s genes we’re finding, over a dozen of them, tell us how to stop neuroinflammation.”

Today you’re going to learn about brand new research that is upending what we think we know about Alzheimer’s and how we’ve been treating the symptoms of the disease for decades.

Enjoy the show! And get more resources at Dave.Asprey/podcasts.

Follow Along with the Transcript

The Rock Star Scientist of Alzheimer’s on How to Stop Neuroinflammation – Dr. Rudolph Tanzi with Dave Asprey – #707

Links/Resources

Website: mghmind.org/faculty/Tanzi
Facebook: facebook.com/RudyETanzi
Twitter: twitter.com/rudytanzi
Instagram: instagram.com/rudy_tanzi/

Key Notes

How can you be a professor and head/chair/director of different geographic locations? – 4:10
What has changed in the understanding of Alzheimer’s and Dementia? – 5:55
How the brain deals with problems with nerves and infection – 8:11
Heart disease vs brain diseases – 9:22
Brain amyloids compared to ageing amyloids – 11:46
Inflammation in the brain is different than in the body – 13:40
Effects of sleep on keeping the brain healthy – 14:14
Genes that switch the function of cells from housekeeping to killer – 15:40
What can be used to reduce inflammation in the brain? – 16:31
Things to do to reduce risk of brain diseases – 18:01
Managing gut bacteria – 22:01
Protecting the brain and lowering inflammation – 24:24
Brain diseases correlated with inflammation – 27:23
Using mini brains to test drugs – 28:56
What will it be like to look back on current treatments for brain diseases? – 30:36
What is the benefit of combining different forms of treatments to lessen brain inflammation? – 33:02
Effects of nicotine? 34:58
Cat’s claw (herb) and mushroom uses – 36:33
What about circadian timing, fasting, and darkness on Alzheimer’s disease? -40:02
What is possible for patients today and in the future? – 46:37
Alzheimer’s in women compared to men – 52:54

Go check out my new book “Super Human: The Bulletproof Plan to Age Backward and Maybe Even Live Forever“ and also “Game Changers“, “Headstrong” and “The Bulletproof Diet” on Amazon and consider leaving a review!

If you like today’s episode, check us out on Apple Podcasts at daveasprey.com/apple and leave us a 5-star rating and a creative review.

Blood Sugar is the Power Energy in Your Video Game Life – Dr. Molly Maloof with Dave Asprey – #706

May 29, 2020 by Dave Asprey

In this episode of Bulletproof Radio, I got to talk with Dr. Molly Maloof about why she wants to bring continuous glucose monitoring (CGM) to the masses and how it can optimize nutrition and health.

CGM is the ultimate lifestyle biomarker. “I don’t think CGM should be a prescription device,” Dr, Molly says. “I think the information about your body should not be behind a pharmacist’s desk. It’s absurd that you have to ask your doctor for information about yourself.”

Her goal is to maximize human potential by radically extending human health span through personal health technologies, scientific wellness and educational media. Dr. Molly teaches a course at Stanford University on strategies for extending health span for longer lifespan. Her concierge medical practice is oriented around optimizing health and improving mitochondrial function.

“It is not acceptable that we are getting so sick so young and we need to ask ourselves ‘what are all the possible causes,’ ” she says. “A lot of it does have to do with how we eat, how we live, how we breathe.” EMFs are in the mix, too.

Dr. Molly’s aim is to redesign the healthcare system by reducing medicine prescriptions and implementing healthy lifestyle principles, like fasting.

“We’re designed to be fasting most of the time,” she says. “We’re not designed to be eating all the time, We have the genetics of scarcity and so abundance is actually damaging to health. Food is fundamental to health. If your food is wrong, your fuel is wrong, you’re screwed.”

She’s a passionate evangelist, empowering advocate and visionary futurist who is pioneering new approaches to personal health. “This is the whole crux of what biohacking is about, right? Like having to hack a system because it won’t give you what you want, why can’t people learn about their bodies? What’s wrong with that?”

Enjoy the show! And get more resources at Dave.Asprey/podcasts.

Follow Along with the Transcript

Blood Sugar is the Power Energy in Your Video Game Life – Dr. Molly Maloof with Dave Asprey – #706

Links/Resources

Website: drmolly.co
Facebook: www.facebook.com/MollyMaloofMD/
Twitter: twitter.com/mollymaloofmd
Instagram: www.instagram.com/drmolly.co
YouTube: www.youtube.com/playlist?list=PLpPdbdIfBt79z7hQVrumCaFOfoqHEDvzE
Adaptive-Iq (Dr. Molly Maloof, founder): adaptive-iq.com

Key Notes

How do you know what the future looks like 5:25
Why the health span messaging is broken 10:22
Obsessed with glucose metabolism 12:27
What cells in the body have the highest concentration of mitochondria 13:15
Mitochondria theory of aging 14:55
Impact sleep has on blood sugar 16:52
Not knowing what foods can cause blood sugar spikes 18:32
The dangers in EMFs 20:20
Some doctors are practicing out-of-date medicine 31:22
Managed care vs. managing health 34:30
Every hallmark of aging is able to be reversed through exercise 36:30
How a body can became more metabolically flexible 40:43
Dave’s three months of zero carbs 43:21
If you feed your gut bacteria without raising your blood sugar, are you still fasting? 45:47
Prebiotics and probiotics 50:33
There are two ways to damage your mitochondria 55:44

If you like today’s episode, check us out on Apple Podcasts at daveasprey.com/apple and leave us a 5-star rating and a creative review.

How Blood Flow Restriction Can Revolutionize Your Fitness – Dr. Jim Stray-Gundersen with Dave Asprey – #705

May 28, 2020 by Dave Asprey

In this episode of Bulletproof Radio, Dr. Jim Stray-Gundersen talks with me about blood flow restriction (BFR) and its practical application for sports, rehabilitation and health conditions. BFR training has broad effects–and benefits– across your biology.

“In 20 minutes, you can get more or less a full body workout and that’s all you need on a daily basis,” he says. “It’s not just about building big muscles, it’s about essentially upgrading all the systems that are involved in exercise.”

Dr. Jim is co-founder and chief medical officer of B Strong, the founder of the S-G Performance Medicine Center, and the Sports Science Advisor for the US Ski and Snowboard Association.

As a physician, researcher and professor, he’s treated thousands of patients and authored thousands of articles over a career spanning more than 40 years. He has extensive experience in the area of sports physiology and has worked with Olympic athletes in various disciplines.

“The lessons that are learned from elite sport can be translated into helping the everyday population live healthier and better lives,” he says.

We go all in on his study and research of altitude training, local and systemic hypoxia, growth hormones, and metabolic crisis–and what all of this has to do with BFR.

Considered a world-renowned expert in blood flow restriction training, Dr. Jim believes that BFR will revolutionize training and rehabilitation everywhere. Listen on to find out how.

Enjoy the show! And get more resources at Dave.Asprey/podcasts.

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Follow Along with the Transcript

How Blood Flow Restriction Can Revolutionize Your Fitness – Dr. Jim Stray-Gundersen with Dave Asprey – #705

Links/Resources

Website: bstrong.training
Facebook: www.facebook.com/bstrongtrainingsystem/
Twitter: twitter.com/bstrongtrain
Instagram: www.instagram.com/bstrongtraining/
YouTube: www.youtube.com/channel/UCKOeqFs_pccpZVAzco4TSVA

Key Notes

Jim’s journey to blood flow restriction training – 3:50
Dave asks what was learned in that training and how has your view of altitude changed over the decades? 07:20
What is the correlation between going slow at high altitudes that can help race performance? 10:00
The affects of blood doping 11:45
Living high for 3-4 weeks is an effective way of increasing your red cell mass which helps your sea level performance increase 13:14
Is there a more accessible way to get these benefits without having to go to high altitudes? 17:00
Lessons learned from elite sports can be translated into helping the everyday population live healthier lives 23:29
Blood flow restriction training explained 26:35
Why is there a physiological change with BLR but not from general hypoxia when used for the same amount of time? 33:30
An injury can heal twice as fast 36:00
Study being done with patients suffering from loss of muscle and how BFR can be beneficial before surgery 39:00
How does the BLR compare for cardiovascular fitness vs. healing and muscle gain? 45:00
Defining VEGF and HIF-1 alpha 46:30
Is there any data on people using BFR to help with chronic fatigue or Lyme disease? 48:25
What does the B Strong system do for the endothelium? 52:00
What is the possible average life expectancy? 59:40

If you like today’s episode, check us out on Apple Podcasts at daveasprey.com/apple and leave us a 5-star rating and a creative review.

Transform Your Indoors with Human Compatible™ Lighting – Robert Soler & Dave Asprey Hack LEDs – #704

May 26, 2020 by Dave Asprey

In this episode of Bulletproof Radio, my guest is Robert Soler, who researches, engineers and designs lighting systems that work best for the human brain and body. We get right into the biology of lighting and why LED lighting has been your No. 1 enemy indoors for years.

As a subject-matter expert for NASA’s Circadian Lighting System onboard the International Space Station, Robert helped design the first LED light for use there. He has since co-founded a NASA spin-off company to bring the same technology to the general public. He’s now vice president of Human Biological Technologies and Research at Biological Innovation and Optimization Systems (BIOS).

Robert and the BIOS team set out to create better lighting to improve human sleep patterns, cognitive function and general health. Their research on circadian lights has been proven to provide benefits in alertness, jet lag, athlete performance, twilight, seasonality, skin response, photoreception, and more.

BIOS is the only truly circadian lighting developed for humans to mimic natural sunlight. “The whole premise is brighter days, darker nights,” Robert says.

BIOS and my company TrueLight have partnered to launch the first consumer lightbulb that works with your circadian rhythm, not against it. We’ve even captured exciting new technology: “We took out the bad blue and re-appropriated into the good blue region, giving those ‘sky blue’ signals that we need and getting rid of the bad blue in the shorter wavelengths,” Robert says.

Listen on to learn how key photoreceptors drive your circadian rhythms, and how this new bulb’s human compatibility features can revolutionize your light and your life.

Enjoy the show!

Follow Along with the Transcript

Transform Your Indoors with Human Compatible Lighting – Robert Soler with Dave Asprey – #704

Links/Resources

Website: https://shoptruelight.com
Website: bioslighting.com
Facebook: facebook.com/bioslighting
Twitter: twitter.com/bioslightingled
Instagram: instagram.com/bioshuman/
Pinterest: pinterest.com/bioslighting/

Key Notes

How Robert came to work at NASA. – 1:54
Blue lIght paradox. – 6:57
How do I cut out the annoying blue but leave enough blue? – 13:19
The effect of brightness versus color on sleep. – 16:13
Interesting things of what lighting does to trick people. – 22:42
Some people who are insanely sensitive to flicker. – 26:12
Melanopsin receptor, ipRGCs. – 35:58
What about TV brightness? How important is it to turn that down? – 44:00
Circadian rhythm. – 45:37
Light on your skin from your LED lights may create more ATP. – 58:04

If you like today’s episode, check us out on Apple Podcasts at daveasprey.com/apple and leave us a 5-star rating and a creative review.

Neuroscience, Mystical Practices, and Transformation with Dr. Joe Dispenza – #703

May 22, 2020 by Dave Asprey

In this episode of Bulletproof Radio, my guest is Dr. Joe Dispenza. He teaches people how to rewire their brains and recondition their bodies to make lasting changes. His work combines neuroscience, epigenetics, and quantum physics to explore the science behind spontaneous remissions and healing.

“I talk about how the mind and body are connected and how we can begin to change who we are and that we’re not hardwired to be a certain way for the rest of our lives, and we’re not doomed by our genes,” Dr. Joe says. “In fact, we’re marvels of adaptability and change.”

He’s an international lecturer, researcher, corporate consultant, author, and educator.

In his advanced workshops around the world, he has partnered with other scientists to perform extensive research on the effects of meditation, including epigenetic testing, brain mapping with electroencephalograms (EEGs), and individual energy field testing with a gas discharge visualization (GDV) machine. His research also includes measuring heart coherence with HeartMath monitors.

“I think there’s power in numbers,” Dr. Joe says. “The higher the amplitude, the higher the energy. And if you get enough people thinking the same way, feeling the same way, doing the same things, and you can get and train them into that frequency.” That’s where the magic of healing and transformation happens.”

In a simple, inspiring, and compassionate way, Dr. Joe shows people how they can take their new knowledge to help heal illnesses, chronic conditions and diseases, and also evolve their consciousness.

“People are beginning to understand that it is more possible when see the evidence in front of them,” Dr. Joe says. “And that’s a footprint in consciousness. And so we have evidence in the scientific world, we have evidence in testimony, and I think evidence is the loudest voice.”

However you’re managing the current global pandemic, you have an opportunity to look within, grow, learn and even speed up your belief in what’s possible.

“So keep doing the work,” Dr. Joe says. “Keep working on yourself. Keep applying it. Try it out. Be a scientist in your life. Experiment. Make it fun. Open up and see if you can begin to produce effects in your life and when you do pay attention to what you did and do it again until you get really good at it.”

Enjoy the show! And get more resources at Dave.Asprey/podcasts.

Follow Along with the Transcript

Neuroscience, Mystical Practices, and Transformation with Dr. Joe Dispenza – #703

Links/Resources

Website: drjoedispenza.com/
Facebook: facebook.com/DrJoeDispenzaOfficialNewsFanPage/
Twitter: twitter.com/drjoedispenza
Instagram: instagram.com/drjoedispenza/
YouTube: youtube.com/user/drjoedispenza/
Books: drjoedispenza.com/collections/books
Meditations: drjoedispenza.com/collections/meditations-english

Key Notes

The mind and body somehow can influence each other to begin to make more permanent changes. – 2:35
We are not separate in space and time. – 3:22
People wearing the monitors, the majority of them went into heart coherence at the exact same time. – 5:15
The heart center has a specific gland that has an endocrine function and an immune function. – 6:31
Over 100,000 people now that have had an exposure to the GOLOV-20. – 8:21
The quantum field is an invisible field of energy and information that exists beyond space and time that connects everything physical. – 9:16
Blown away by the dramatic changes we’re seeing in the way the cell functions. – 10:26
There’s some kind of experience where they feel a greater level of love than they’ve ever felt in their entire life. – 14:25
The autonomic nervous system processing high amplitudes of gamma in a very coherent way is sending a very, very orderly signal to every cell and tissue in the body. And when we see that there are immediate quantum effects. – 14:51
We have evidence in the scientific world, we have evidence in testimony, and I think evidence is the loudest voice. – 20:56
They’re faster than the speed of light. That’s a quantum phenomenon. – 24:32
The more in wholeness or connectedness, we are more divine. So maybe it’s just a function of language. – 29:00
But it’s not chemical. It’s electrical. – 32:42
Do something in addition to what you’re doing to see if you can find the new input into the system. 37:53
The soul is what connects us to singularity. – 40:34
What’s going on neurologically when people are crystallizing when they need it? – 48:40

If you like today’s episode, check us out on Apple Podcasts at daveasprey.com/apple and leave us a (hopefully) 5-star rating and a creative review.

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Design Your Own ‘Mindapps’ to Expand Your Smarts & Creativity – Thomas Roberts, Ph.D., with Dave Asprey – #702

May 21, 2020 by Dave Asprey

In this episode of Bulletproof Radio, my guest is Thomas Roberts, Ph.D., who’s devoted a nearly 50-year career to the study of psychedelics. Tom has developed “mind design” technologies and practices he calls mindapps.

Just like writing and installing apps in our electronic devices, we can construct “mindapps” and install them in our brain-mind complex, he says. And just like digital apps add capabilities to our devices, mindapps can expand our intellectual capacity and creative abilities.

Tom’s mindapps also offer benefits for artistic performance, mystical and spiritual experience, and scientific research by improving creativity, open-mindedness, problem solving, and inner-brain connections—the ultimate performance hacking!

“There are things we can install in our brain/mind complex that allow it to do new things and to do things more strongly,” Tom says. “I’m not saying that a mindapp is like artificial intelligence in electronical sense. I’m just taking that idea and transferring it over to things. Now, my favorite, of course, is psychedelics, but it includes brain stimulation, hypnosis, breathing techniques, biofeedback, chanting, yoga, hypnosis, on and on. All of these are mindapps that we can install and use our brain/mind complex in different ways.”

We’re intentionally redesigning our own minds, he explains, and lays it all out in his most recent book: Mindapps: Multistate Theory and Tools for Mind Design. We talk about mindapps and how they connect to consciousness and psychedelic science.

Tom is a professor emeritus of educational psychology at Northern Illinois University and a former visiting scientist at Johns Hopkins, He’s presented around the world on consciousness and psychedelic science. For 32 years, he taught Foundations of Psychedelic Studies, which was the world’s first university-cataloged psychedelic course.

Enjoy the show! And get more resources at Dave.Asprey/podcasts.

Follow Along with the Transcript

Design Your Own ‘Mindapps’ to Expand Your Smarts & Creativity – Thomas Roberts, Ph.D., with Dave Asprey – #702

Links/Resources

About Thomas B. Roberts, Ph.D.: niu.academia.edu/ThomasRoberts
Books & Interviews: innertraditions.com/author/thomas-b-roberts
More About Thomas B.Roberts, Ph.D.
LinkedIn: linkedin.com/in/dr-thomas-b-roberts-8b463213

Key Notes

50 years of looking at this stuff. What was the impetus? – 1:26
I changed like a big aircraft carrier, a little at a time. – 6:20
So I called that Bicycle Day. – 8:57
All of these are mind apps that we can install and use our brain/mind complex in different ways. – 11:01
What’s your favorite psychedelic? – 14:44
What happens when we combine, let’s say, LSD with hypnosis and brain stimulation? – 17:01
I think this has to be studied very carefully, probably in very small amounts. – 19:03
If you change a setting in your brain, it may very well be invisible to you. – 21:00
Different mind/body effects will have different effects on people at different times. – 22:25
Why do hallucinogens work for some people in a certain way, but not for others? – 24:00
I use mind/body state in the sense that Charlie Tart means, an altered state of consciousness and mind/body functioning. – 28:19
What happens when you invent new states? How will perception vary in those state? – 30:01
What is your take on microdosing versus doing a full dose experience from that or any of the other hallucinogens? Pros and cons? – 32:44
If you could go to 7-Eleven and get your tab of acid, would that be a good thing or a bad thing? – 39:07
I’m interested in the use of the entheogenic use of psychedelics. I use the word entheogen only to apply to religious and spiritual uses. – 41:19
Once the Army Medical Corp and the Veterans Administration Hospital get into using MDMA with PTSD, that’s definitely going to be a big advance. – 45:36
Consilience. It’s the idea of taking all the theory and facts that we have on different areas, all the way from let’s say subatomic physics through physics, and chemistry, and biology, and psychology, and the social sciences and linking them all together in one big structure, one structure of ideas. – 49:53
Towards the end of the book, you talk about that achieving the philosophers mind. What is the philosopher’s mind? – 54:43

If you like today’s episode, check us out on Apple Podcasts at daveasprey.com/apple and leave us a 5-star rating and a creative review.

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The Rock Star Scientist of Alzheimer’s on How to Stop Neuroinflammation – Dr. Rudolph Tanzi with Dave Asprey – #707

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Links/Resources

Key Notes

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Key Notes

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Key Notes

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